71016-95-0

Basic information

• Product Name: Cyclopentanecarboxylic anhydride
• CAS NO: 71016-95-0
• Molecular Formula: C₁₂H₁₈O₃
• Molecular Weight: 210.2695
• Mol File: 71016-95-0.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 323.578°C at 760 mmHg
• Flash Point: 145.498°C
• Density: 1.138g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.507
• CAS DataBase Reference: Cyclopentanecarboxylic anhydride(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopentanecarboxylic anhydride(71016-95-0)
• EPA Substance Registry System: Cyclopentanecarboxylic anhydride(71016-95-0)

Safety Data

• Hazardous Substances Data: 71016-95-0(Hazardous Substances Data)

Upstream product

• 4524-93-0 Cyclopentanecarboxylic acid chloride 
• 3400-45-1 cyclopentanecarboxylic acid 
• 108-24-7 acetic anhydride 

Downstream Products

• 18531-94-7 (R)-1,1'-Bi-2-naphthol 
• 18531-99-2 (S)-[1,1']-binaphthalenyl-2,2'-diol 
• 41295-00-5 p-tert.-Butylphenylcyclopentan 

Relevant articles and documents

ADAMANTYLMETHYLAMINE DERIVATIVE AND USE THEREOF AS PHARMACEUTICAL

The present invention provides a pharmaceutical composition for treating or preventing a cognitive disease or disorder, comprising a compound represented by Formula (I), an enantiomer thereof, a diastereomer thereof, or a pharmaceutically acceptable salt thereof.

Nickel-Catalyzed Decarboxylative Alkenylation of Anhydrides with Vinyl Triflates or Halides

Decarboxylative cross-coupling of aliphatic acid anhydrides with vinyl triflates or halides was accomplished via nickel catalysis. This methodology works well with a broad array of substrates and features abundant functional group tolerance. Notably, our approach addresses the issue of safe and environmental installation of methyl or ethyl group into molecular scaffolds. The method possesses high chemoselectivity toward alkyl groups when aliphatic/aromatic mixed anhydrides are involved. Furthermore, diverse ketones could be modified with our strategy.

Isothiourea-Catalysed Regioselective Acylative Kinetic Resolution of Axially Chiral Biaryl Diols

An operationally simple isothiourea-catalysed acylative kinetic resolution of unprotected 1,1′-biaryl-2,2′-diol derivatives has been developed to allow access to axially chiral compounds in highly enantioenriched form (s values up to 190). Investigation of the reaction scope and limitations provided three key observations: i) the diol motif of the substrate was essential for good conversion and high s values; ii) the use of an α,α-disubstituted mixed anhydride (2,2-diphenylacetic pivalic anhydride) was critical to minimize diacylation and give high selectivity; iii) the presence of substituents in the 3,3′-positions of the diol hindered effective acylation. This final observation was exploited for the highly regioselective acylative kinetic resolution of unsymmetrical biaryl diol substrates bearing a single 3-substituent. Based on the key observations identified, acylation transition state models have been proposed to explain the atropselectivity of this kinetic resolution.