71100-72-6

Basic information

• Product Name: ibu-dmt-deoxyguanosine triester
• Synonyms: 3'-Guanylic acid, 5'-O-(bis(4-methoxyphenyl)phenylmethyl)-2'-deoxy-N-(2-methyl-1-oxopropyl)-, 4-chlorophenyl 2-cyanoethyl ester
• CAS NO: 71100-72-6
• Molecular Formula: C₄₄H₄₄ClN₆O₁₀P
• Molecular Weight: 883.29
• EINECS: 275-192-4
• Mol File: 71100-72-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: ibu-dmt-deoxyguanosine triester(CAS DataBase Reference)
• NIST Chemistry Reference: ibu-dmt-deoxyguanosine triester(71100-72-6)
• EPA Substance Registry System: ibu-dmt-deoxyguanosine triester(71100-72-6)

Safety Data

• Hazardous Substances Data: 71100-72-6(Hazardous Substances Data)

Upstream product

• 68892-41-1 5'-O-dimethoxytrityl-N-isobutyryldeoxyguanosine 
• 32666-92-5 p-chlorophenyl phosphorodichloridite 
• 109-78-4 3-Hydroxypropionitrile 
• 772-79-2 4-chlorophenylphosphorodichloridate 
• 69507-62-6 (p-chlorophenyl) (β-cyanoethyl) phosphorochloridate 

Downstream Products

• 93403-70-4 <(MeO)2Tr>G^ibupTOAc 
• 81551-80-6 C₄₃H₄₇Cl₂N₁₁O₁₅P₂ 
• 90827-16-0 C₃₉H₄₂Cl₂N₈O₁₅P₂ 
• 69924-11-4 C₆₄H₆₅Cl₂N₁₁O₁₇P₂ 
• 73591-24-9 5'-O-(bis(4-methoxyphenyl)phenylmethyl)-P-(4-chlorophenyl)thymidylyl-(3'->5')-2'-deoxy-N-(2-methyl-1-oxopropyl)-3'-guanylic acid, 4-chlorophenyl 2-cyanoethyl ester 
• 71002-59-0 N²-isobutyryl-2'-deoxy-[3']guanylic acid 4-chloro-phenyl ester 2-cyano-ethyl ester 
• 71100-63-5 C₄₁H₄₀ClN₅O₁₀P^(1-) 
• 84379-96-4 4-chlorophenyl 5'-O-(4,4'-dimethoxytrityl)-N²-isobutyryl-2'-deoxyguanosin-3'-yl phosphate triethylammonium salt 

Relevant articles and documents

Synthesis of Deoxyoligonucleotide Linker Fragments for Genetic Engineering Using Improved Preparative and Analytical Techniques

For studies on the expression of recombinant DNA, linker fragments have been prepared which serve to introduce specific points of cleavage on the DNA as well as the protein level.Such linkers were designed for cyanogen bromide as well as for collagenase cleavage of fused proteins.The preparation was done according to the triester synthesis scheme using improved and simpler routes to functionalized dinucleotide building blocks.Field desorption mass spectrometry was used as a routine tool for the identification and control of the purity of these units.

PREPARATION RAPIDE DES MONONUCLEOSIDES-3' MONOPHOSPHATE PROTEGES UTILISABLES EN SYNTHESE OLIGONUCLEOTIDIQUE

Fully protected mononucleotides are prepared by the action of parachlorophenylphosphodichloridite in THF on the corresponding nucleosides followed by oxidation with iodine.