711016-23-8

Basic information

• Product Name: Benzeneacetamide, 3-bromo-N-(5,6,7,8-tetrahydro-7-hydroxy-1-naphthalenyl)-
• CAS NO: 711016-23-8
• Molecular Formula: C18H18BrNO2
• Molecular Weight: 360.25
• Mol File: 711016-23-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzeneacetamide, 3-bromo-N-(5,6,7,8-tetrahydro-7-hydroxy-1-naphthalenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetamide, 3-bromo-N-(5,6,7,8-tetrahydro-7-hydroxy-1-naphthalenyl)-(711016-23-8)
• EPA Substance Registry System: Benzeneacetamide, 3-bromo-N-(5,6,7,8-tetrahydro-7-hydroxy-1-naphthalenyl)-(711016-23-8)

Safety Data

• Hazardous Substances Data: 711016-23-8(Hazardous Substances Data)

Upstream product

• 624729-74-4 8-amino-3,4-dihydronaphthalen-2(1H)-one 
• 624729-66-4 8-amino-1,2,3,4-tetrahydronaphthalen-2-ol 
• 1878-67-7 3-Bromophenylacetic acid 

Downstream Products

• 711016-20-5 2-biphenyl-3-yl-N-(7-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl)acetamide 

Relevant articles and documents

TETRAHYDRO-NAPHTHALENE AND UREA DERIVATIVES

This invention relates to tetrahydro-naphthalene and urea derivatives and salts thereof which are useful as active ingredients of pharmaceutical preparations. The tetrahydro-naphthalene and urea derivatives of the present invention have vanilloid receptor (VR1) antagonistic activity, and can be used for the prophylaxis and treatment of diseases associated with VR1 activity, in particular for the treatment of urological diseases or disorders, such as detrusor overactivity (overactive bladder), urinary incontinence, neurogenic detrusor oeractivity (detrusor hyperflexia), idiopathic detrusor overactivity (detrusor instability), benign prostatic hyperplasia, and lower urinary tract symptoms; chronic pain, neuropathic pain, postoperative pain, rheumatoid arthritic pain, neuralgia, neuropathies, algesia, nerve injury, ischaemia, neurodegeneration, stroke, and inflammatory disorders such as asthma and chronic obstructive pulmonary (or airways) disease (COPD). BHC 03 2 001-Foreign-Countries - 66 - BHC 03 2 001-Foreign-Countries - 65 -