71107-19-2 Usage
Description
2-Oxo-5-vinylpyrrolidine-3-carboxamide is a chemical compound derived from (2E)-1,4-Dibromo-2-butene (D425545), which is utilized as a reagent in the preparation of diaminoalkenes through a copper-mediated diamination reaction. 2-oxo-5-vinylpyrrolidine-3-carboxamide plays a significant role in various applications across different industries due to its unique properties and reactivity.
Uses
Used in Pharmaceutical Industry:
2-Oxo-5-vinylpyrrolidine-3-carboxamide is used as an intermediate compound for the synthesis of various pharmaceutical products. Its role in the preparation of diaminoalkenes makes it a valuable component in the development of new drugs and therapeutic agents.
Used in Analytical Chemistry:
In the field of analytical chemistry, 2-Oxo-5-vinylpyrrolidine-3-carboxamide is employed for the separation of vigabatrin from other compounds using high-performance liquid chromatography (HPLC) and macroporous polymeric columns. This application aids in the accurate analysis and identification of vigabatrin, which is crucial for quality control and research purposes.
Used in Chemical Research:
2-Oxo-5-vinylpyrrolidine-3-carboxamide serves as a key compound in chemical research, particularly in the study of copper-mediated diamination reactions. Its involvement in the synthesis of diaminoalkenes contributes to the advancement of chemical knowledge and the development of novel chemical processes and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 71107-19-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,1,0 and 7 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 71107-19:
(7*7)+(6*1)+(5*1)+(4*0)+(3*7)+(2*1)+(1*9)=92
92 % 10 = 2
So 71107-19-2 is a valid CAS Registry Number.
InChI:InChI=1/C7H10N2O2/c1-2-4-3-5(6(8)10)7(11)9-4/h2,4-5H,1,3H2,(H2,8,10)(H,9,11)
71107-19-2Relevant articles and documents
A convenient approach for vinylation reaction in the synthesis of 5-vinyl-2-pyrrolidinone, a key intermediate of vigabatrin
Karumanchi, Kishore,Natarajan, Senthil Kumar,Gadde, Sunil,Vanchanagiri, Krishna
, p. 2035 - 2039 (2020/01/02)
A convenient, safe and cost-effective method for carrying out the key vinylation of 5-ethoxy-2-pyrrolidinone (8) in the preparation of 5-vinyl-2-pyrrolidinone (2) in the presence of potassium carbonate is described. This present procedure is developed by replacing inherently hazardous ethyl magnesium bromide with inexpensive and eco-friendly potassium carbonate. The reaction was performed on a multi-gram scale, with vinyl magnesium bromide as the vinylation reagent, in an 81% yield to give the 5-vinyl-2-pyrrolidinone with excellent purity and without the need for chromatography.
Process for making 4-aminohex-5-enoic acid
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, (2008/06/13)
Novel compounds of the following general formula are useful in the preparation of 4-aminohex-5-enoic acid and 4-aminohex-5-ynoic acid which are useful pharmacological agents: STR1 wherein R1 is hydroxy, amino, or tert-butoxy.
