71140-51-7

Basic information

• Product Name: (R)-(-)-MEPHENYTOIN
• Synonyms: (R)-(-)-5-Ethyl-3-methyl-5-phenyl-2,4-imidazolidinedione, (R)-(-)-5-Ethyl-3-methyl-5-phenylhydantoin;(5R)-5-ethyl-3-methyl-5-phenyl-imidazolidine-2,4-dione;(5R)-5-ethyl-3-methyl-5-phenylimidazolidine-2,4-dione;(R)-(-)-MEPHENYTOIN;(R)-MEPHENYTOIN;(R)-(-)-5-ETHYL-3-METHYL-5-PHENYL-2,4-IMIDAZOLIDINEDIONE;(R)-(-)-5-ETHYL-3-METHYL-5-PHENYLHYDANTOIN;(R)-5-ETHYL-3-METHYL-5-PHENYLHYDANTOIN
• CAS NO: 71140-51-7
• Molecular Formula: C₁₂H₁₄N₂O₂
• Molecular Weight: 218.25
• Product Categories: Hydantoins & Derivatives;Intermediates & Fine Chemicals;Pharmaceuticals;Heterocycles;Hydantoins and Derivatives
• Mol File: 71140-51-7.mol
• Article Data: 4

Chemical Properties

• Melting Point: 137-138°C
• Appearance: off-white/
• Density: 1.154g/cm³
• Refractive Index: 1.541
• Storage Temp.: 2-8°C
• Solubility: Acetone, Chloroform, DMSO (Slightly), Methanol (Slightly)
• CAS DataBase Reference: (R)-(-)-MEPHENYTOIN(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(-)-MEPHENYTOIN(71140-51-7)
• EPA Substance Registry System: (R)-(-)-MEPHENYTOIN(71140-51-7)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 71140-51-7(Hazardous Substances Data)

Usage

Chemical Properties

White Crystalline Solid

Uses

Different sources of media describe the Uses of 71140-51-7 differently. You can refer to the following data:
1. An anticonvulsant agent.
2. (R)-Mephenytoin is used as an anticonvulsant agent

InChI:InChI=1/C12H14N2O2/c1-3-12(9-7-5-4-6-8-9)10(15)14(2)11(16)13-12/h4-8H,3H2,1-2H3,(H,13,16)/t12-/m1/s1

Upstream product

• 2671-99-0 (+)-Mephobarbital 
• 33875-36-4 2-Isocyanato-2-phenyl-butyronitrile 
• 75356-45-5 1-(1-Cyano-1-phenyl-propyl)-3-methyl-urea 
• 50-12-4 mephenytoin 

Downstream Products

• 61837-65-8 4'-hydroxyl-S-mephenytoin 
• 33875-38-6 (R)-2‐amino‐2‐phenylbutyric acid 

Relevant articles and documents

Stereospecificity of the photoinduced conversion of methylphenobarbital to mephenytoin

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Chromatographic Resolutions of Racemates, XI. Comparison of Optically Active Polyamides and Cellulose Triacetate

On optically active polyacrylic and polymethacrylic amides (1a-e) as well as on microcrystalline cellulose triacetate (2), numerous racemates including drugs are separated at least partially, the amide 4f completely on cellulose triacetate.By repeated chromatography on the polyamide 1a, (+)- and (-)-mandelic acid (4a) and (+)-hexobarbital (9d) also were obtained optically pure.