7115-46-0

Basic information

• Product Name: 1-DEOXY-1-(METHYLAMINO)-D-GALACTITOL
• Synonyms: 1-DEOXY-1-(METHYLAMINO)-D-GALACTITOL;1-DEOXY-1-(METHYLAMINO)-D-GALACTITOL 9&
• CAS NO: 7115-46-0
• Molecular Formula: C₇H₁₇NO₅
• Molecular Weight: 195.21
• Mol File: 7115-46-0.mol
• Article Data: 1

Chemical Properties

• Melting Point: 133-136 °C(lit.)
• Boiling Point: 490.4±45.0 °C(Predicted)
• Appearance: /
• Density: 1.375±0.06 g/cm3(Predicted)
• Refractive Index: 1.555
• PKA: 13.47±0.20(Predicted)
• CAS DataBase Reference: 1-DEOXY-1-(METHYLAMINO)-D-GALACTITOL(CAS DataBase Reference)
• NIST Chemistry Reference: 1-DEOXY-1-(METHYLAMINO)-D-GALACTITOL(7115-46-0)
• EPA Substance Registry System: 1-DEOXY-1-(METHYLAMINO)-D-GALACTITOL(7115-46-0)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 7115-46-0(Hazardous Substances Data)

Usage

Description

1-DEOXY-1-(METHYLAMINO)-D-GALACTITOL is a chemical compound derived from D-galactose, a monosaccharide sugar. It is characterized by the presence of a methylamino group attached to the first carbon, which distinguishes it from other related compounds. This unique structure endows it with specific properties that make it suitable for various applications in different industries.

Uses

Used in Pharmaceutical Industry:
1-DEOXY-1-(METHYLAMINO)-D-GALACTITOL serves as a starting material for the preparation of sulfoximine-nicotine derivatives. These derivatives act as kinase inhibitors and are valuable in the treatment of proliferative diseases, such as cancer, by targeting and inhibiting the activity of specific enzymes involved in cell growth and division.
Additionally, 1-DEOXY-1-(METHYLAMINO)-D-GALACTITOL is utilized in the synthesis of novel tricyclic benzodiazepine carboxamides. These compounds function as tocolytic oxytocin receptor antagonists, playing a crucial role in managing preterm labor by blocking the effects of oxytocin, a hormone responsible for uterine contractions.

InChI:InChI=1/C7H17NO5/c1-8-2-4(10)6(12)7(13)5(11)3-9/h4-13H,2-3H2,1H3/t4-,5+,6+,7-/m0/s1

Upstream product

• 2280-44-6 D-Glucose 
• 74-89-5 methylamine 
• 59-23-4 D-Galactose 

Downstream Products

• 7115-58-4 1--phenyl-thiocarbamoyl)-amino>-1-desoxy-D-dulcit 
• 7057-03-6 1--phenylcarbamoyl)-amino>-1-desoxy-D-dulcit 
• 265121-04-8 Fosaprepitant dimeglumine 
• 439080-84-9 1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-{10-[methyl-(2,3,4,5,6-pentahydroxyhexyl)amino]decyloxy}phenyl)azetidin-2-one 
• 439080-82-7 1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-{8-[methyl-(2,3,4,5,6-pentahydroxyhexyl)amino]octyloxy}phenyl)azetidin-2-one 
• 439080-80-5 1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-{6-[methyl-(2,3,4,5,6-pentahydroxyhexyl)amino]hexyloxy}phenyl)azetidin-2-one 
• 439080-78-1 1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-{5-[methyl-(2,3,4,5,6-pentahydroxyhexyl)amino]pentyloxy}phenyl)azetidin-2-one 
• 439080-76-9 1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-{4-[methyl-(2,3,4,5,6-pentahydroxyhexyl)amino]butoxy}phenyl)azetidin-2-one 
• 34081-28-2 D_r-1t_F,2t_F,3r_F,4-tetraacetoxy-1cat_F-((5S)-3-methyl-2t-phenyl-oxazolidin-5r-yl)-butane 
• 74-93-1 methylthiol 
• 113224-26-3 C₉H₁₇N₅O₇ 
• 113224-27-4 C₁₀H₁₇N₅O₅ 
• 7115-51-7 1--1-desoxy-D-dulcit 
• 7115-63-1 1--1-desoxy-D-dulcit 

Relevant articles and documents

Process for the preparation of N-alkypolyhydroxyalkylamines from monoalkylamine and reducing sugar

Aqueous, alcoholic or aqueous-alcoholic solutions of a monoalkylamine and a reducing sugar are simultaneously injected into a mixing unit and the two solutions are mixed under turbulence in the mixing unit for 6 seconds to 5 minutes at a temperature of 25 to 60° C. and a pressure of 50 to 90 bar. The mixture is then added to a hydrogenation reactor and hydrogenated with hydrogen in the presence of a hydrogenation catalyst. An alkylpolyhydroxyalkylamine is obtained in high yield and with high purity.