71186-59-9

Basic information

• Product Name: Benzaldehyde, 5-methoxy-2-(2-propenyloxy)-
• CAS NO: 71186-59-9
• Molecular Formula: C11H12O3
• Molecular Weight: 192.214
• Mol File: 71186-59-9.mol
• Article Data: 20

Chemical Properties

• CAS DataBase Reference: Benzaldehyde, 5-methoxy-2-(2-propenyloxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 5-methoxy-2-(2-propenyloxy)-(71186-59-9)
• EPA Substance Registry System: Benzaldehyde, 5-methoxy-2-(2-propenyloxy)-(71186-59-9)

Safety Data

• Hazardous Substances Data: 71186-59-9(Hazardous Substances Data)

Upstream product

• 672-13-9 2-hydroxy-5-methoxybenzaldehyde 
• 4392-24-9 Cinnamyl bromide 
• 150-76-5 4-methoxy-phenol 
• 1048108-36-6 (2-(allyloxy)-5-methoxyphenyl)methanol 
• 106-95-6 allyl bromide 

Downstream Products

• 934569-91-2 1-(2-allyloxy-5-methoxyphenyl)hept-2-yn-1-ol 
• 1048108-36-6 (2-(allyloxy)-5-methoxyphenyl)methanol 
• 1358108-26-5 C₁₈H₁₉NO₃ 
• 1358108-17-4 C₁₈H₁₉NO₃ 
• 1615224-41-3 C₂₈H₃₅BF₂N₄O₄ 
• 1615224-44-6 C₂₇H₃₁BF₂N₄O₄ 
• 1615224-38-8 C₃₁H₃₉BF₂N₄O₄ 

Relevant articles and documents

Discovery of seneciobipyrrolidine derivatives for the amelioration of glucose homeostasis disorders through 4E-BP1/Akt/AMPK signaling activation

Modulating the glucose transport in skeletal muscle is a promising strategy for ameliorating glucose homeostasis disorders. However, the complicated mechanisms of glucose transport make it difficult to find compounds therapeutically relevant molecular mechanisms of action, while phenotypic screening is thought to be an alternative approach to mimic the cell state of interest. Here, we report (±)-seneciobipyrrolidine (1a) is first found to enhance glucose uptake in L6 myotubes through phenotype-based screening. Further SAR investigation led to the identfication of compound A27 (EC50 = 2.7 μM). Proteomiic analysis discloses the unique function mechanism of A27 through upregulating the level of the eukaryotic translation initiation factor 4E-binding protein 1 (4E-BP1), subsequently enhancing the Akt and AMPK phosphorylation, thereby promoting the glucose uptake. Chronic oral administration of A27 significantly lowers blood glucose and improves glucose tolerance in db/db mice. This work is new research on seneciobipyrrolidine derivatives, providing a promising avenue for ameliorating glucose homeostasis.

Rim-Differentiated C5-Symmetric Tiara-Pillar[5]arenes

The synthesis of "rim-differentiated" C5-symmetric pillar[5]arenes, whose two rims are decorated with different chemical functionalities, has remained a challenging task. This is due to the inherent statistical nature of the cyclization of 1,4-

Cycloisomerization between Aryl Enol Ether and Silylalkynes under Ruthenium Hydride Catalysis: Synthesis of 2,3-Disubstituted Benzofurans

Metal-catalyzed cycloisomerization reactions of 1,n-enynes have become conceptually and chemically attractive processes in the search for atom economy, which is a key subject of current research. However, metal-catalyzed cycloisomerization between aryl enol ether and silylalkynes has not been developed. The ruthenium hydride complex catalyzed cycloisomerization between aryl enol ether and silylalkynes is reported to give benzofurans having useful functional groups, vinyl and trimethylsilylmethyl, on the 2- and 3-positions, respectively.