71198-74-8

Basic information

• Product Name: 5(4H)-Oxazolone, 4-[[4-(acetyloxy)phenyl]methylene]-2-phenyl-, (4Z)-
• CAS NO: 71198-74-8
• Molecular Formula: C18H13NO4
• Molecular Weight: 307.306
• Mol File: 71198-74-8.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: 5(4H)-Oxazolone, 4-[[4-(acetyloxy)phenyl]methylene]-2-phenyl-, (4Z)-(CAS DataBase Reference)
• NIST Chemistry Reference: 5(4H)-Oxazolone, 4-[[4-(acetyloxy)phenyl]methylene]-2-phenyl-, (4Z)-(71198-74-8)
• EPA Substance Registry System: 5(4H)-Oxazolone, 4-[[4-(acetyloxy)phenyl]methylene]-2-phenyl-, (4Z)-(71198-74-8)

Safety Data

• Hazardous Substances Data: 71198-74-8(Hazardous Substances Data)

Upstream product

• 495-69-2 Hippuric Acid 
• 127-09-3 sodium acetate 
• 123-08-0 4-hydroxy-benzaldehyde 
• 878-00-2 4-formylphenyl acetate 
• 1199-01-5 2-phenylazlactone 
• 98-88-4 benzoyl chloride 
• 108-24-7 acetic anhydride 

Downstream Products

• 15398-31-9 1c-(4-acetoxy-phenyl)-5-phenyl-(3rN)-6-oxa-4-aza-spiro[2.4]hept-4-en-7-one 
• 374922-51-7 N-benzyl-2-(benzamido)-3-(4-acetoxyphenyl)acrylamide 
• 1384247-45-3 4-(4-hydroxybenzylidene)-1-benzyl-2-phenylimidazol-5-one 
• 150890-98-5 3-[(Z)-3-(4-Acetoxy-phenyl)-2-benzoylamino-acryloylamino]-propionic acid 
• 4000-69-5 4-(3-acetyl-4-hydroxy-benzylidene)-2-phenyl-4H-oxazol-5-one 
• 156-38-7 4-hydroxyphenylacetate 
• 77362-30-2 Acetic acid 4-((1S,2S,3R)-2-benzoyl-7-oxo-5-phenyl-6-oxa-4-aza-spiro[2.4]hept-4-en-1-yl)-phenyl ester 
• 77362-30-2 Acetic acid 4-((1R,2R,3R)-2-benzoyl-7-oxo-5-phenyl-6-oxa-4-aza-spiro[2.4]hept-4-en-1-yl)-phenyl ester 

Relevant articles and documents

Concise Modular Synthesis of Thalassotalic Acids A-C

The novel N-acyldehydrotyrosine analogues known as thalassotalic acids A-C were isolated from a marine bacterium by Deering et al. in 2016. These molecules were shown to have tyrosinase inhibition activity and thus are an attractive set of molecules for further study and optimization. To this end, a concise and modular synthesis has been devised and executed to produce thalassotalic acids A-C and two unnatural analogues. This synthesis has confirmed the identity and inhibitory data of thalassotalic acids A-C, more potent synthetic analogues (IC50 = 65 μM), and provides a route for further structure-activity relationship studies to optimize these molecules.

DUAL EMISSION FLUORESCENT COMPOUNDS

The invention relates to a dual emission fluorescent compound comprising a chromophore suitable for exhibiting an emission at a first wavelength from an excited state; wherein the compound further comprises one or more groups suitable for inducing a structural rearrangement in the molecule on formation of the excited state, wherein the structural rearrangement stabilises at least a second electromagnetic emission at a second wavelength, such that dual emission is observable at room temperature. Such dual emission allows for the super sensitive ratiometric quantification of analytes.

New compounds having skin whitening, antioxidant and PPAR activity, and medical use thereof

PURPOSE: A novel compound with skin whitening, antioxidation, and PPAR activation effects, and a medical use thereof are provided to be used for a pharmaceutical composition or a cosmetic product. CONSTITUTION: A compound is denoted by chemical formula 1. A skin whitening composition contains the compound as an active ingredient. An antioxidative composition for preventing or treating oxidative diseases contains the compound of chemical formula 1 as an active ingredient. The oxidative diseases are selected among skin aging, pigmentation, wrinkling, psoriasis, or eczema. The composition prevents or treats diseases which are regulated by PPAR(peroxisome proliferator-activated receptor) activity. The PPAR includes PPAR alpha or PPAR gamma.