7122-93-2

Basic information

• Product Name: [1,1'-Bicyclohexyl]-3-one
• Synonyms: 3-Cyclohexylcyclohexanone
• CAS NO: 7122-93-2
• Molecular Formula: C12H20O
• Molecular Weight: 180.29
• Mol File: 7122-93-2.mol
• Article Data: 32

Chemical Properties

• CAS DataBase Reference: [1,1'-Bicyclohexyl]-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: [1,1'-Bicyclohexyl]-3-one(7122-93-2)
• EPA Substance Registry System: [1,1'-Bicyclohexyl]-3-one(7122-93-2)

Safety Data

• Hazardous Substances Data: 7122-93-2(Hazardous Substances Data)

Usage

Description

[1,1'-Bicyclohexyl]-3-one, a bicyclic ketone with the molecular formula C12H18O, is a chemical compound known for its excellent stability and high melting and boiling points. It is commonly used as a building block in the synthesis of various organic compounds due to its unique chemical properties.

Uses

Used in Organic Synthesis:
[1,1'-Bicyclohexyl]-3-one is used as a building block for the synthesis of various organic compounds, contributing to its versatility in different fields.
Used in Fragrance Industry:
[1,1'-Bicyclohexyl]-3-one is used as a component in the production of fragrances, enhancing the scent profiles of various products.
Used in Pharmaceutical Industry:
[1,1'-Bicyclohexyl]-3-one is utilized in the pharmaceutical industry, likely due to its stability and unique properties, which can be beneficial in the development of new drugs.
Used as a Solvent:
[1,1'-Bicyclohexyl]-3-one is used as a solvent in some chemical reactions, providing a stable and effective medium for these processes.
Used in Food Industry:
[1,1'-Bicyclohexyl]-3-one is also used as a flavoring agent in the food industry, adding unique taste profiles to various products.

Upstream product

• 930-68-7 cyclohexenone 
• 7565-57-3 cyclohexylzinc(II) bromide 
• 98-89-5 Cyclohexanecarboxylic acid 
• 126812-30-4 1,3-dioxoisoindolin-2-yl cyclohexanecarboxylate 
• 125764-09-2 tetraethylammonium bis<α,α-bis(trifluoromethyl)benzenemethanolato(2-)-C²,O>cyclohexylsilicate 
• 108-94-1 cyclohexanone 
• 2044-08-8 1-bromocyclohex-1-ene 
• 76886-59-4 [1,1'-bi(cyclohexan)]-1'-en-3-one 
• 108-85-0 1-bromocyclohexane 
• 100-66-3 methoxybenzene 
• 109-99-9 tetrahydrofuran 
• 626-62-0 Cyclohexyl iodide 
• 97-94-9 triethyl borane 
• 121883-35-0 cyclohexylzinc iodide 

Relevant articles and documents

Photocatalytic Giese-Type Reaction with Alkylsilicates Bearing C,O-Bidentate Ligands

Herein, a photocatalytic Giese-type reaction with alkylsilicates bearing C,O-bidentate ligands as stable alkyl radical precursors has been reported. The alkylsilicates were prepared in one step from organometallic reagents. Not only primary, secondary, and tertiary alkyl radicals, but also elusive methyl radicals, could be generated by using the present reaction system. The generated radicals were trapped by electron-deficient olefins bearing various functional groups to give the desired alkyl adducts. The silicon byproduct can be recovered after the photoreaction. The radical generation process was investigated by theoretical calculations, which provided an insight into the facile generation of methyl radicals from methylsilicate bearing C,O-bidentate ligands.

Acridine Photocatalysis: Insights into the Mechanism and Development of a Dual-Catalytic Direct Decarboxylative Conjugate Addition

Conjugate addition is one of the most synthetically useful carbon-carbon bond-forming reactions; however, reactive carbon nucleophiles are typically required to effect the addition. Radical conjugate addition provides an avenue for replacing reactive nucleophiles with convenient radical precursors. Carboxylic acids can serve as simple and stable radical precursors by way of decarboxylation, but activation to reactive esters is typically necessary to facilitate the challenging decarboxylation. Here, we report a direct, dual-catalytic decarboxylative radical conjugate addition of a wide range of carboxylic acids that does not require acid preactivation and is enabled by the visible light-driven acridine photocatalysis interfaced with an efficient copper catalytic cycle. Mechanistic and computational studies provide insights into the roles of the ligands and metal species in the dual-catalytic process and the photocatalytic activity of substituted acridines.

Direct β-Alkenylation of Ketones via Pd-Catalyzed Redox Cascade

A direct β-alkenylation of simple ketones with alkenyl bromides is reported via a Pd-catalyzed redox cascade strategy. The reaction is redox neutral and directing-group-free, in the absence of strong acids or bases. Both cyclic and linear ketones are suitable substrates, and various alkenyl bromides can be coupled. The resulting β-alkenyl ketones are readily derivatized through diverse alkene functionalization.