712280-04-1

Basic information

• Product Name: (E)-4-(4-Methoxy-phenyl)-1-(3-methyl-pyrazin-2-yl)-but-3-en-2-ol
• CAS NO: 712280-04-1
• Molecular Weight: 270.331
• Mol File: 712280-04-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-4-(4-Methoxy-phenyl)-1-(3-methyl-pyrazin-2-yl)-but-3-en-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-4-(4-Methoxy-phenyl)-1-(3-methyl-pyrazin-2-yl)-but-3-en-2-ol(712280-04-1)
• EPA Substance Registry System: (E)-4-(4-Methoxy-phenyl)-1-(3-methyl-pyrazin-2-yl)-but-3-en-2-ol(712280-04-1)

Safety Data

• Hazardous Substances Data: 712280-04-1(Hazardous Substances Data)

Upstream product

• 5910-89-4 2,3-dimethylpyrazine 
• 24680-50-0 4-methoxy-trans-cinnamaldehyde 

Downstream Products

• 712280-17-6 cis,trans-2-[(4-methoxyphenyl)buta-1,3-dienyl]-3-methylpyrazine 
• 712280-20-1 trans,trans-2-[(4-methoxyphenyl)buta-1,3-dienyl]-3-methylpyrazine 

Relevant articles and documents

Novel intramolecular cyclization of 2-(buta-1,3-dienyl)-3-methylpyrazines and 3-(buta-1,3-dienyl)-4-methyl-1,2,5-oxadiazoles into 5H-cycloheptapyrazines and 4H-cyclohepta-1,2,5-oxadiazoles

2-(Buta-1,3-dienyl)-3-methylpyrazines (5) and 3-(buta-1,3-dienyl)-4-methyl- 1,2,5-oxadiazoles (10) were synthesized starting from base-induced reaction of 2,3-dimethylpyrazine or 3,4-dimethyl-1,2,5-oxadiazole with α,β- unsaturated carbonyls. The thus obtained heteroaromatics bearing a butadienyl moiety and a methyl at the adjacent position underwent intramolecular cyclization by the action of LDA to give the corresponding heteroaromatics fused with a seven-membered ring [7 (8)] and [11 (12)] in moderate to high yields.