71254-90-5

Basic information

• Product Name: 1-acetyl-3,4,4-trimethyl-4,5-dihydro-1H-imidazol-3-ium
• CAS NO: 71254-90-5
• Molecular Formula: C₈H₁₅N₂O
• Molecular Weight: 155.217
• Mol File: 71254-90-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-acetyl-3,4,4-trimethyl-4,5-dihydro-1H-imidazol-3-ium(CAS DataBase Reference)
• NIST Chemistry Reference: 1-acetyl-3,4,4-trimethyl-4,5-dihydro-1H-imidazol-3-ium(71254-90-5)
• EPA Substance Registry System: 1-acetyl-3,4,4-trimethyl-4,5-dihydro-1H-imidazol-3-ium(71254-90-5)

Safety Data

• Hazardous Substances Data: 71254-90-5(Hazardous Substances Data)

Usage

Derivative of

Thiamine (vitamin B1)

Solubility

Water-soluble salt

Uses

Dietary supplement, nutrient fortifier in food products

Role in the body

Energy metabolism, carbohydrate metabolism, nerve function

Treatment

Thiamine deficiency, certain neurological disorders

Chemical classification

Quaternary ammonium compound

Charge

Positively charged nitrogen atom

Potential applications

Drug delivery systems, pharmaceutical formulations, biochemical and pharmaceutical applications

Upstream product

• 2305-59-1 4,4-dimethyl-2-imidazoline 
• 71254-88-1 1-acetyl-4,4-dimethyl-Δ²-imidazoline 
• 74-88-4 methyl iodide 

Downstream Products

• 73955-62-1 1-acetyl-2-(4-methoxy-phenyl)-3,4,4-trimethyl-imidazolidine 
• 89367-44-2 1-acetyl-2-phenyl-3,4,4-trimethylimidazolidine 

Relevant articles and documents

MODELS OF FOLATE COENZYMES-VII SYNTHESIS AND CARBON TRANSFER REACTIONS OF N5,N10-METHENYL AND N5,N10-METHYLENETETRAHYDROFOLATE MODELS

Carboxylate esters react with 1,2-diaminoethanes to yield imidazolines, which upon consecutive reaction with acetic anhydride or tosyl chloride and methyl iodide give imidazolinium salts that serve as models of N5,N10-(CH+)-tetrahydrofolate (THF) coenzymes (7a,b and 18a,b).Reduction of the latter salts with sodium borohydride or reaction with anions (R-) give the corresponding 5,10--THF models.Mono- and bifunctional nucleophiles react with 18a,b to yield carbon-transfer products. 6-Alkylamino-1,3-dimethyluracils react with 1-tosyl-3,4,4-trimethylimidazolidine (the reduction product of 18b), in the presence of acetic acid, to form carbon-transfer products via a mechanism which bears close analogy to the mechanism of action of thymidylate synthetase.