7127-73-3 Usage
General Description
2,3,6,7-Tetrademethoxytylophorin is a chemical compound found in the plant Tylophora ovata. It belongs to the class of phenanthroindolizidine alkaloids and has been the subject of scientific research for its potential pharmacological properties. Studies have suggested that 2,3,6,7-Tetrademethoxytylophorin exhibits anti-inflammatory, anticancer, and immunomodulatory effects, making it a promising candidate for the development of new pharmaceutical drugs. Additionally, this compound has shown potential in modulating autophagy, a cellular process involved in the maintenance of cellular homeostasis and the prevention of various diseases. Its diverse biological activities have sparked interest in further exploring its potential applications in medicine and biotechnology.
Check Digit Verification of cas no
The CAS Registry Mumber 7127-73-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,1,2 and 7 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 7127-73:
(6*7)+(5*1)+(4*2)+(3*7)+(2*7)+(1*3)=93
93 % 10 = 3
So 7127-73-3 is a valid CAS Registry Number.
7127-73-3Relevant articles and documents
Expedient synthesis and structure-activity relationships of phenanthroindolizidine and phenanthroquinolizidine alkaloids
Chuang, Ta-Hsien,Lee, Shiow-Ju,Yang, Cheng-Wei,Wu, Pei-Lin
, p. 860 - 867 (2006)
The total synthesis of alkaloids phenanthroindolizidine 1a, tylophorine 1b, and phenanthroquinolizidine 1c, has been achieved in 46%, 49%, and 42% overall yield, respectively, starting from the corresponding phenanthrene-9- carboxaldehyde. Compound 1c exhibited potent inhibition activity in three human cancer cell lines, with IC50 values ranging from 104 to 130 nM. The structure-activity relations of these alkaloids and some of their synthetic intermediates against the three cell lines were also described. The Royal Society of Chemistry 2006.
