71280-25-6Relevant articles and documents
Roles of two basic nitrogen atoms in 1-substituted 4-(1,2- diphenylethyl)piperazine derivatives in production of opioid agonist and antagonist activities
Natsuka, Kagayaki,Nishikawa, Yoshinori,Nakamura, Hideo
, p. 1790 - 1793 (2007/10/03)
To ascertain roles of the two basic nitrogen atoms in 1-substituted 4- [2-(3-hydroxyphenyl)-1-phenylethyl]piperazine derivatives (1) in the expression of opioid agonist and antagonist activities, a methine group (CH) was isosterically substituted for nitr