7133-85-9

Basic information

• Product Name: 2H-1,3-Benzoxazine-2,4(3H)-dione, 3-(4-chlorophenyl)-
• CAS NO: 7133-85-9
• Molecular Formula: C14H8ClNO3
• Molecular Weight: 273.675
• Mol File: 7133-85-9.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2H-1,3-Benzoxazine-2,4(3H)-dione, 3-(4-chlorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-1,3-Benzoxazine-2,4(3H)-dione, 3-(4-chlorophenyl)-(7133-85-9)
• EPA Substance Registry System: 2H-1,3-Benzoxazine-2,4(3H)-dione, 3-(4-chlorophenyl)-(7133-85-9)

Safety Data

• Hazardous Substances Data: 7133-85-9(Hazardous Substances Data)

Upstream product

• 611-20-1 salicylonitrile 
• 88220-36-4 2-<(4-chlorophenyl)aminocarbonyloxy>benzonitrile 
• 104-12-1 p-chlorphenylisocyanate 
• 3679-63-8 4'-chlorosalicylanilide 
• 108-23-6 isopropyl chloroformate 
• 88220-42-2 4-imino>-3-(4-chlorophenyl)-2H-1,3-benzoxazin-2-one 
• 541-41-3 chloroformic acid ethyl ester 
• 533-58-4 2-Iodophenol 
• 201230-82-2 carbon monoxide 

Relevant articles and documents

Palladium-Catalyzed Cyclocarbonylation of o-Iodophenols and 2-Hydroxy-3-iodopyridine with Heterocumulenes: Regioselective Synthesis of Benzo[e]-1,3-oxazin-4-one and Pyrido[3,2-e]-1,3-oxazin-4-one Derivatives

Benzo[e]-1,3-oxazin-2-imine-4-ones (3) were synthesized by cyclocarbonylation of o-iodophenols with carbodiimides in the presence of a catalytic amount of a palladium catalyst and 1,4-bis-(diphenylphosphino)butane under CO pressure. Product yields are dep

NEW GROUPS OF POTENTIAL ANTITUBERCULOTICS: 3-ARYL-2H,4H-BENZOXAZINE-2,4-DIONES. COMPARISON OF THE TOPLISS APPROACH WITH REGRESSION ANALYSIS

3-Phenyl-2H,4H-benzoxazine-2,4-dione (I) and its derivatives II - XI, substituted on the phenyl ring, can be regarded as a new group of potential antituberculotics.Their activity increases with increasing electron-accepting properties of the substituents.Introduction of bromine into the position 6 also positively influences the activity.The compounds are active in vitro against Mycobacterium tuberculosis and M. kansasii.The activity of some of them (VIII, IX) exceeds that of commercial tuberculostatics used as standards.

Studies on 2-hydroxythiobenzamide and 2-hydroxythiobenzanilide. 1. Synthesis of the compounds

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