71350-68-0

Basic information

• Product Name: 2-AMINO-1-BIPHENYL-4-YL-ETHANONE HYDROCHLORIDE
• Synonyms: 2-AMINO-1-BIPHENYL-4-YL-ETHANONE HYDROCHLORIDE;2-AMINO-1-(1,1'-BIPHENYL-4-YL)ETHANONE HYDROCHLORIDE
• CAS NO: 71350-68-0
• Molecular Formula: C₁₄H₁₃NO*ClH
• Molecular Weight: 247.72
• Mol File: 71350-68-0.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-AMINO-1-BIPHENYL-4-YL-ETHANONE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-1-BIPHENYL-4-YL-ETHANONE HYDROCHLORIDE(71350-68-0)
• EPA Substance Registry System: 2-AMINO-1-BIPHENYL-4-YL-ETHANONE HYDROCHLORIDE(71350-68-0)

Safety Data

• Statements: 36
• Safety Statements: 26
• Hazardous Substances Data: 71350-68-0(Hazardous Substances Data)

Usage

Chemical class

biphenyl derivatives

Physical appearance

white to off-white solid

Uses

organic synthesis, pharmaceutical research, intermediate in dye production, antioxidant production, other chemical products

Form

hydrochloride salt form for stability and solubility in aqueous solutions.

Upstream product

• 127118-90-5 C₁₆H₁₃NO₃ 
• 135-73-9 2-Bromo-4'-phenylacetophenone 
• 86217-82-5 1-(biphenyl-4-yl)ethanamine 
• 18197-26-7 sodium diformamide 
• 5520-63-8 (4-phenyl-phenacyl)-hexamethylenetetraminium; bromide 

Downstream Products

• 98421-86-4 N-(4-phenyl-phenacyl)-[1]naphthamide 
• 131745-25-0 3-amino-2-[1,1'-biphenyl]-4-yl-6-fluoro-4-quinolinecarboxylic acid 
• 51127-66-3 6-(5-biphenyl-4-yl-oxazol-2-yl)-2-phenyl-benzo[de]isoquinoline-1,3-dione 
• 17064-13-0 5-biphenyl-4-yl-2-naphthalen-1-yl-oxazole 
• 101274-76-4 5-biphenyl-4-yl-2-methylthiazole 
• 97814-05-6 Toluene-4-sulfonate4-(5-biphenyl-4-yl-oxazol-2-yl)-1-ethyl-pyridinium; 
• 97814-09-0 1-Benzyl-4-(5-biphenyl-4-yl-oxazol-2-yl)-pyridinium; chloride 
• 97509-04-1 C₄₂H₂₈N₂O₂ 
• 108783-71-7 2-(4-Carbomethoxyphenyl)-5-(4-phenylphenyl)oxazole 
• 108783-83-1 Acid Chloride of 2-(4-Carboxyphenyl)-5-(4-phenylphenyl)oxazole 
• 108783-78-4 2-(4-Carboxyphenyl)-5-(4-phenylphenyl)oxazole 
• 108783-89-7 2-(4-Carbamidophenyl)-5-(4-phenylphenyl)oxazole 
• 94993-78-9 5-Biphenyl-4-yl-3-methyl-6,7-dihydro-1H-pyrazolo[4,3-e][1,4]diazepin-8-one 
• 115846-62-3 3-Biphenyl-4-yl-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole; hydrochloride 

Relevant articles and documents

SYNTHESIS OF LUMINOPHORIC DERIVATIVES OF PBD BASED ON 2,5-DIARYL SUBSTITUTED THIAZOLES AND OXAZOLES

The Friedel-Crafts acylation of 2-(biphenyl-4-yl)-5-phenyl-1,3,4-oxadiazole (PBD) with hippuryl chloride has been used to prepare the derivative V which on cyclization with POCl3 or P4S10 gives the respective oxazole (or thiazole) derivative of PBD, XIa or XIb.The reaction of carboxylic acid II with 4-(ω-aminoacetyl)biphenyl in the presence of CDI gives N-acyl-α-aminoketone VII; the analogous compound VI has been prepared by acylating ω-aminoacetophenone with acyl chloride III.The cyclization of these compounds gives bifluorophores Xa - Xd.

A Convenient Synthesis of Aminomethyl Ketones (α-Amino Ketones)

Several N,N-diformylaminomethyl ketones 3 were prepared by treating the respective bromomethylketone 1 with sodium diformylamide in acetonitrile at room temperature.This reaction produced from N-formylaminomethyl ketones 4 when ethanol was used as the solvent.One of the formyl groups of N,N-difomylaminomethyl ketones was selectively removed by using a catalytic amount of sodium or potassium hydroxide in alcohol to the corresponding N-formylaminomethyl ketones 4.The formyl groups of both N,N-diformyl- and N-formylaminomethyl ketones could be easily removed by either5percent hydrochloric acid in ethanol or 6N hydrochloric acid to give the corresponding aminomethyl ketone hydrochlorides 5.These reactions are general and give high yield of the products.