71408-03-2

Basic information

• Product Name: 5-acetyl-2-amino-4-hydroxybenzonitrile
• Synonyms: benzonitrile, 5-acetyl-2-amino-4-hydroxy-
• CAS NO: 71408-03-2
• Molecular Formula: C₉H₈N₂O₂
• Molecular Weight: 176.172
• Mol File: 71408-03-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 422.3°C at 760 mmHg
• Flash Point: 209.2°C
• Density: 1.35g/cm³
• Vapor Pressure: 9.9E-08mmHg at 25°C
• Refractive Index: 1.62
• CAS DataBase Reference: 5-acetyl-2-amino-4-hydroxybenzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 5-acetyl-2-amino-4-hydroxybenzonitrile(71408-03-2)
• EPA Substance Registry System: 5-acetyl-2-amino-4-hydroxybenzonitrile(71408-03-2)

Safety Data

• Hazardous Substances Data: 71408-03-2(Hazardous Substances Data)

Upstream product

• 71043-35-1 3-methoxymethylenepentane-2,4-dione 
• 109-77-3 malononitrile 
• 33884-41-2 ethoxylideneacetylacetone 

Downstream Products

• 115651-29-1 5-Acetyl-2-amino-4-hydroxybenzoesaeure 
• 115651-27-9 5-Acetyl-2-amino-4-hydroxybenzoesaeureamid 
• 115651-31-5 5-Acetyl-2-chlor-4-hydroxybenzonitril 
• 115651-37-1 2-Amino-5-<1-(ethoxyimino)ethyl>-4-hydroxybenzonitril 
• 115651-38-2 5-<1-(Allyloxyimino)ethyl>-2-amino-4-hydroxy-benzonitril 

Relevant articles and documents

Synthesis of Benzoic Acid Derivatives from 3-Ethoxymethylene-2,4-alkanediones and Malononitrile

Reaction of the 3-ethoxymethylene-2,4-alkanediones 1a-c with malononitrile (2) gives the benzonitrile derivatives 3a-c.Compounds 4a-d are obtained by acid or basic hydrolysis of the nitrile group of 3a-c, Sandmeyer reaction leads to the halogenated benzonitriles 5a-f.Compounds 6a,b are available from 3a and O-ethyl- and O-allylhydroxylamine hydrochloride.