71449-22-4

Basic information

• Product Name: L-Cysteine, S-[(4-methoxyphenyl)methyl]-, methyl ester, hydrochloride
• CAS NO: 71449-22-4
• Molecular Formula: C12H17NO3S.ClH
• Molecular Weight: 291.799
• Mol File: 71449-22-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: L-Cysteine, S-[(4-methoxyphenyl)methyl]-, methyl ester, hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: L-Cysteine, S-[(4-methoxyphenyl)methyl]-, methyl ester, hydrochloride(71449-22-4)
• EPA Substance Registry System: L-Cysteine, S-[(4-methoxyphenyl)methyl]-, methyl ester, hydrochloride(71449-22-4)

Safety Data

• Hazardous Substances Data: 71449-22-4(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 18942-46-6 N-(tert-butyloxycarbonyl)-S-(4-methoxybenzyl)cysteine 
• 2544-31-2 S-(4-methoxybenzyl)-L-cysteine 
• 77-76-9 2,2-dimethoxy-propane 

Downstream Products

• 97721-57-8 N-t-Boc-Leu-(p-MeOBzl)Cys-OMe 
• 93394-73-1 N-(tert-butyloxycarbonyl)phenylalanyl-S-(4-methoxybenzyl)cysteinyl methyl ester 
• 83176-23-2 N-tert-butyloxycarbonyl-S-(4-methoxybenzyl)cysteine methyl ester 
• 93394-75-3 N-(tert-butyloxycarbonyl)-S-(4-methoxybenzyl)cysteinyl-glycyl-glycyl-glycyl-phenylalanyl-S-(4-methoxybenzyl)cysteine methyl ester 
• 93394-74-2 phenylalanyl-S-(4-methoxybenzyl)cysteine methylester 
• 97721-62-5 N-Z-(S-Bzl)Cys-Gln-Phe-Phe-Gly-Leu-(p-MeOBzl)Cys-NH₂ 
• 97721-54-5 C₅₂H₆₇N₉O₉S₂ 
• 97721-60-3 (S)-2-Amino-4-methyl-pentanoic acid [(R)-1-carbamoyl-2-(4-methoxy-benzylsulfanyl)-ethyl]-amide; compound with trifluoro-acetic acid 
• 97721-58-9 N-t-Boc-Leu-(p-MeOBzl)Cys-NH₂ 

Relevant articles and documents

INDOLE AND INDAZOLE DERIVATIVES HAVING A CELL-, TISSUE- AND ORGAN-PRESERVING EFFECT

The present invention relates to a composition for preserving cells, tissues and organs, comprising as an active ingredient indole and indazole compounds of formula (1), or a pharmaceutically acceptable salt or isomer thereof, which are effective for preventing injury of organs, isolated cell systems or tissues caused by cold storage, transplant operation or post-transplantation reperfusion; a preservation method; and a preparation method of the composition.

INDOLE COMPOUNDS AS AN INHIBITOR OF CELLULAR NECROSIS

The present invention relates to new indole compounds, pharmaceutically acceptable salts or isomers thereof which are useful for the prevention or treatment of cellular necrosis and necrosis-associated diseases. The present invention also relates to a method and a composition for the prevention or treatment of cellular necrosis and necrosis-associated diseases, comprising said indole compounds as an active ingredient.

Oxidative Deblocking of the 4-Methoxybenzyl Thioether Protecting Group: Application to the Directed Synthesis of Poly-cystinyl Peptides

The 4-methoxybenzyl thioether protecting group is deblocked efficiently by oxidation with the homogeneous electron transfer agent tris(4-bromophenyl)ammoniumyl (2.+) leading to the disulfide in high yields.S-(4-methoxybenzyl)cysteine derivatives like 9 in this way can be transformed into the corresponding cystine derivatives like 10 in 90percent yield.Many N and carboxy protecting groups like the Boc and Z group and tert-butyl or benzyl ester functions are stable under the cleavage conditions.On the other hand the 4-methoxybenzyl thioether protecting group is totally unaffected by the conditions for oxidative deblocking of the S-trityl functions by either iodine or rhodanolysis.This opens up new opportunities for the directed synthesis of cystinyl peptides with more than one intra- or interchain disulfide bridge.Application of the new method to the synthesis of a cystine peptide with one intrachain S-S-bridge and a double-chain biscystinyl peptide is reported.