71468-10-5Relevant articles and documents
A facile one-pot synthesis of benzimidazoles from 2-nitroanilines by reductive cyclization
Liu, Zheng,Li, Haihong,Zhao, Qingjie,Shen, Jingshan
scheme or table, p. 1907 - 1911 (2009/04/06)
A facile one-pot process to prepare benzimidazole derivatives is described. Reductive cyclization of a serial of 2-nitroanilines with orthoesters in the presence of Pd/C in methanol at room temperature, which is promoted by a catalytic amount of acetic acid, affords the corresponding benzimidazole derivatives in high yields.