7147-77-5Relevant articles and documents
A highly selective dual-channel chemosensor for mercury ions: Utilization of the mechanism of intramolecular charge transfer blocking
Zhang, You Ming,Qu, Wen Juan,Gao, Guo Ying,Shi, Bing Bing,Wu, Gui Yuan,Wei, Tai Bao,Lin, Qi,Yao, Hong
, p. 5075 - 5080 (2014)
In this study, we developed a novel chemosensor (ATS) that contains the 5-(4-nitrophenyl)-2-furan group and α-naphthylamine for the dual-channel sensing of mercury ions. Under attack from mercury ions, the probe undergoes a blocked process; moreover, it broke the intramolecular charge transfer (ICT) state of the chemosensor, which can be confirmed by 1H NMR, IR and MS studies. We designed this probe to produce a significant change in the color and fluorescence intensity that can achieve naked eye recognition. The experimental results proved that the 5-(4-nitrophenyl)-2-furan group is a very good chromophore. In addition, the ICT state inhibited the fluorescence of naphthylamine. The fluorescent intensity changed significantly when naphthylamine was released. Moreover, high selectivity experiments revealed that the fluorescent sensor is specific to mercury ions even with interference by high concentrations of other metal ions. The test strips based on ATS were fabricated, which could act as a convenient and efficient mercury ion test kit. This journal is
New calamitic mesogens derived from a furan ring: Synthesis, characterization and study of their mesomorphic behavior
Abdulnabi, Nabih M.,Abdul Razzaq Al-Obaidy, Mazin M.,Tomi, Ivan Hameed R.,Jaffer, Hamed Jasim
, (2021)
A new series of mesogens bearing furan moiety, 4-[((5-(4-nitrophenyl)furan-2-yl)methylene)amino]phenyl 4-alkoxybenzoate (Ca-k) was synthesized by different organic methodologies. These mesogens possess an alkoxy chain at one arm and a nitro group at the opposite arm in addition to various linkages (imine and ester). Their chemical structures have been identified by various essential characterization techniques: infrared spectroscopy (FTIR), 1H and 13C nuclear magnetic resonance (NMR), and electron ionization-mass spectrometer (EI-MS). The thermal transition and optical behavior properties of the homologous series have been studied by differential scanning calorimetry (DSC) and a polarizing optical microscope (POM), respectively. The compounds of this series (Ca-Ck) displayed liquid crystalline phases, and all mesogens exhibited an enantiotropic nematic phase (N) in heating and cooling cycles except the compounds (Cd, Ce and Cf), which showed a monotropic nematic phase in the cooling cycle only. Additionally, the last member of this series (Ck) showed a smectic A (SmA) phase in addition to the nematic phase. The obtained results showed that the enantiotropic and monotropic mesogenic properties, in addition to the thermal stability of the mesophase for all mesogens, have been influenced thoroughly by increasing the number of carbon atoms in the terminal alkoxy tail and the nitro group on the other side. In addition to these results, these mesogens could be affected by other factors, such as polarity and polarizability of the linkages and other connected groups in the molecules. The liquid crystalline behaviors of the target compounds have been studied and discussed extensively and compared structurally in related literature.
Benzimidazole-based turn-on fluorescence probe developed for highly specific and ultrasensitive detection of hypochlorite ions in living cells
Yang, Yi,Cheng, Siyao,Dong, Wei
, p. 1377 - 1384 (2021/05/05)
Hypochlorite (ClO?), as one of the active oxygen species (ROS), plays an essential role in the cellular defence system and organism immunity. In this paper, we successfully synthesized a new ‘turn-on’ fluorescent probe BMF based on benzimidazole and characterized it by spectroscopic methods. The designed probe can quickly respond to ClO? with the obvious colour change from pink to colourless. Notably, the probe BMF exhibited almost no fluorescence, but showed strong fluorescence after adding ClO?, including an excellent fluorescence turn-on effect. The fluorescence turn-on phenomenon of BMF was attributed to the strong oxidation of ClO?, which severed the connecting double bond and disrupted the intramolecular charge transfer (ICT) system, plus light-induced electron transfer effect between the fluorophore and the recognition group was discontinued. In addition, the cytotoxicity assay showed that the probe had lower cytotoxicity. Based on these advantages, we demonstrated that probe BMF might be a good candidate for detecting ClO? in biological systems.
Carbon–Carbon Bond Formation for the Synthesis of 5-Aryl-2-Substituted Furans Catalyzed by K3[Fe(CN)6]
Ambika,Singh, Pradeep Pratap
, (2021/10/05)
An efficient method for the carbon–carbon bond formation at C-5 position of 2-substituted furans to provide a range of π-diverse 5-aryl-2-substituted furan derivatives in 58–80% yield has been reported. The method employs several advantages such as use of catalytic amount of K3[Fe(CN)6] under mild conditions and short reaction time with high yields. Also, a variety of anilines with a variety of functional groups can be employed for the synthesis of 5-aryl-2-substituted furans. Graphic Abstract: [Figure not available: see fulltext.]