71719-62-5Relevant articles and documents
Lewis acid promoted cyclization of enyne triesters and diesters
Yamazaki, Shoko,Yamada, Kuriko,Yamabe, Shinichi,Yamamoto, Kagetoshi
, p. 2889 - 2901 (2007/10/03)
Reactions of enynes with three or two ester groups (1-4) in the presence of halogen-ligand Lewis acids gave cyclized products with halide incorporation (5-8) with high generality. The cyclization process was also analyzed in a theoretical study. Facile isomerization and dehydrohalogenation of five-membered products 5 and 8 by Al2O3 or Et3N were also observed; this process introduces conjugated moieties into the products.