71720-27-9 Usage
Description
1,2-Dimethoxy-3-isopropylbenzene, also known as 3-Isopropylveratrole, is an organic compound that serves as an intermediate in the synthesis of Miltirone (M344500), an active component found in Salvia miltiorrhiza.
Uses
Used in Pharmaceutical Industry:
1,2-Dimethoxy-3-isopropylbenzene is used as an intermediate in the synthesis of Miltirone, a potential phytotherapeutic agent for the treatment of alcohol dependence. Miltirone has been shown to inhibit the increase in the abundance of the mRNA for the α4 subunit of the GABAA receptor induced by ethanol withdrawal in cultured hippocampal neurons.
Check Digit Verification of cas no
The CAS Registry Mumber 71720-27-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,7,2 and 0 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 71720-27:
(7*7)+(6*1)+(5*7)+(4*2)+(3*0)+(2*2)+(1*7)=109
109 % 10 = 9
So 71720-27-9 is a valid CAS Registry Number.
71720-27-9Relevant articles and documents
An expedient synthesis of isopropyl anisoles and veratroles
Yli-Kauhaluoma, Jari T.,Janda, Kim D.
, p. 4509 - 4510 (2007/10/02)
Isopropyl-substituted anisoles and veratroles were obtained in high yields (89-93%) on the aqueous work-up of the reaction of 3-(methoxyphenyl)-2-oxopropanoic acids with iodomethane and potassium hydroxide in dimethyl sulfoxide.
Synthesis of gossypol analogues
Ognyanov,Petrov,Tiholov,Mollov
, p. 353 - 360 (2007/10/02)
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AN APPROACH TO TAXODIONE INVOLVING BIOMIMETIC POLYENE CYCLIZATION METHODOLOGY
Johnson, William S.,Shenvi, Ashok B.,Boots, Sharon G.
, p. 1397 - 1404 (2007/10/02)
A novel synthesis of 11,12-dimethoxyabieta-8,11,13-triene (4), involving the biomimetic cyclization of allylic alcohol 5 is described.This represents a formal total synthesis of taxodione (1), a tumor-inhibitory diterpenoid quinone methide.Treatment of th