717918-03-1Relevant articles and documents
Synthesis of Benzyl Amines via Copper-Catalyzed Enantioselective Aza-Friedel-Crafts Addition of Phenols to N -Sulfonyl Aldimines
Shikora, Jonathan M.,Chemler, Sherry R.
supporting information, p. 2133 - 2137 (2018/04/30)
A new copper-catalyzed enantioselective aza-Freidel-Crafts reaction between phenols and N-sulfonyl aldimines that provides chiral secondary benzylamines in good to excellent yields and excellent enantioselectivities (up to 99% ee) is disclosed. In particular, excellent scope with alkylimines was observed for the first time. The synthetic utility of the products was demonstrated in the first enantioselective synthesis of a dual orexin receptor antagonist, a compound that contains an amine-bearing stereocenter adjacent to a bis-ortho-functionalized arene.
Aza-Reformatsky reaction promoted by catalytic samarium diiodide: Synthesis of β-amino esters or amides
Rodríguez-Solla, Humberto,Díaz-Pardo, Ainhoa,Concellón, Carmen,Del Amo, Vicente
, p. 1709 - 1712 (2014/08/05)
The synthesis of β-amino esters or amides has been achieved from moderate to high yields from the reaction of imines and α-halo esters or amides promoted by catalytic amounts of samarium diiodide in the presence of magnesium turnings as co-reductant. A me
A novel imido-transfer reaction of aldehydes with Ph3P=NTs using RuCl2(PPh3)3 as catalyst
Jain, Suman L.,Sharma, Vishal B.,Sain, Bir
, p. 4341 - 4343 (2007/10/03)
(N-Tosylimino)triphenylphosphorane (Ph3P=NTs) was found to be an efficient imido-transfer reagent for the imidation of a variety of aldehydes using RuCl2(PPh3)3 as the catalyst.
