71793-51-6 Usage
General Description
2-METHOXY-5-NITROPHENYL ISOTHIOCYANATE is a chemical compound with the molecular formula C8H6N2O3S. It is a derivative of isothiocyanate, which is characterized by the presence of an isothiocyanate group (-N=C=S) attached to a phenyl ring containing a methoxy and nitro substituent. 2-METHOXY-5-NITROPHENYL ISOTHIOCYANATE is commonly used in organic synthesis and chemical reactions, particularly in the preparation of heterocyclic compounds and organic intermediates. It is also utilized in the pharmaceutical industry for the development of novel drugs and as a building block in the production of chemicals and materials. 2-METHOXY-5-NITROPHENYL ISOTHIOCYANATE has potential applications in various fields due to its unique chemical properties and reactivity.
Check Digit Verification of cas no
The CAS Registry Mumber 71793-51-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,7,9 and 3 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 71793-51:
(7*7)+(6*1)+(5*7)+(4*9)+(3*3)+(2*5)+(1*1)=146
146 % 10 = 6
So 71793-51-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H6N2O3S/c1-13-8-3-2-6(10(11)12)4-7(8)9-5-14/h2-4H,1H3
71793-51-6Relevant articles and documents
Design and synthesis of novel N-[3-(benzimidazol-2-ylamino)phenyl]amine and N-[3-(benzoxazol-2-ylamino)phenyl]amine derivatives as potential anticancer agents
Kumar, Honnavalli Yogish,Murumkar, Prashant R.,Pawar, Vijay,Srinivasan, B. P.,Yadav, M. R.
, (2021/10/20)
In this contribution, we report the design, synthesis and cytotoxicity studies of a series of N-[3-(benzimidazol-2-yl-amino)phenyl]amine and N-[3-(benzoxazol-2-ylamino)phenyl]amine derivatives. In vitro cytotoxicity assay of 26 selected compounds was carried out at National Cancer Institute (NCI), USA. Out of them, compounds 10e (NSC D-762842/1) and 11s (NSC D-764942/1) have shown remarkable cytotoxicity with GI50 values ranging between “0.589–14.3?μM” and “0.276–12.3?μM,” respectively, in the representative nine subpanels of human tumor cell lines. Further, flow cytometry analysis demonstrated that compound 10e exerted cell cycle arrest at G2/M phase and showed dose-dependent enhancement in apoptosis in K-562 leukemia cancer cells.
