71800-37-8 Usage
General Description
(DES-ARG10,LEU9)-KALLIDIN is a peptide that belongs to the kinin family of vasoactive peptides. It is derived from kininogen, a plasma protein, and is a potent vasodilator and inducer of smooth muscle contraction. This peptide plays a role in the regulation of blood pressure, inflammation, and pain perception. It is also involved in the pathophysiology of various diseases including hypertension, heart failure, and renal dysfunction. Additionally, (DES-ARG10,LEU9)-KALLIDIN has been shown to exert its effects through interaction with specific receptors, leading to the activation of signaling pathways that mediate its biological actions. Overall, (DES-ARG10,LEU9)-KALLIDIN is an important molecule in the field of cardiovascular and inflammatory research with potential therapeutic implications.
Check Digit Verification of cas no
The CAS Registry Mumber 71800-37-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,8,0 and 0 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 71800-37:
(7*7)+(6*1)+(5*8)+(4*0)+(3*0)+(2*3)+(1*7)=108
108 % 10 = 8
So 71800-37-8 is a valid CAS Registry Number.
71800-37-8Relevant articles and documents
Orally active peptidic bradykinin B1 receptor antagonists engineered from a cyclotide scaffold for inflammatory pain treatment
Wong, Clarence T. T.,Rowlands, Dewi K.,Wong, Chi-Hang,Lo, Theodore W. C.,Nguyen, Giang K. T.,Li, Hoi-Yeung,Tam, James P.
, p. 5620 - 5624 (2012)
Edible: By grafting natural peptide antagonists onto the cyclotide kalata B1, orally active peptides were engineered, which are potentially useful therapeutics for the treatment of inflammatory pain. For example, the entire loop 6 of kalata B1 was replaced with the peptidic bradykinin B1 receptor antagonist DALK (red in scheme) to obtain the cyclic bradykinin antagonist ckb-kal. Copyright
