718642-08-1

Basic information

• Product Name: 1,3,2-Dioxaborolane, 2-(3-fluorophenyl)-
• CAS NO: 718642-08-1
• Molecular Formula: C8H8BFO2
• Molecular Weight: 165.96
• Mol File: 718642-08-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1,3,2-Dioxaborolane, 2-(3-fluorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,2-Dioxaborolane, 2-(3-fluorophenyl)-(718642-08-1)
• EPA Substance Registry System: 1,3,2-Dioxaborolane, 2-(3-fluorophenyl)-(718642-08-1)

Safety Data

• Hazardous Substances Data: 718642-08-1(Hazardous Substances Data)

Upstream product

• 768-35-4 3-fluorophenylboronic acid 
• 107-21-1 ethylene glycol 

Downstream Products

• 871817-29-7 C₈H₈BFO 

Relevant articles and documents

Hydrolytically-Resistant Boron-Containing Therapeutics And Methods Of Use

Compositions and methods of use of boron derivatives, including benzoxaboroles, benzazaboroles and benzthiaboroles, as therapeutic agents for treatment of diseases caused by fungi, yeast, bacteria or viruses are disclosed, as well as methods for synthesis of said agents and compositions thereof.

Discovery of a new boron-containing antifungal agent, 5-fluoro-1,3-dihydro- 1-hydroxy-2,1-benzoxaborole (AN2690), for the potential treatment of onychomycosis

A structure-activity relationship investigation for a more efficacious therapy to treat onychomycosis, a fungal infection of the toe and fingernails, led to the discovery of a boron-containing small molecule, 5-fluoro-1,3-dihydro- 1-hydroxy-2,1-benzoxaborole (AN2690), which is currently in clinical trials for onychomycosis topical treatment.