719277-22-2

Basic information

• Product Name: Benzenemethanamine, N-ethyl-4-(trifluoromethoxy)-
• CAS NO: 719277-22-2
• Molecular Formula: C10H12F3NO
• Molecular Weight: 219.207
• Mol File: 719277-22-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzenemethanamine, N-ethyl-4-(trifluoromethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanamine, N-ethyl-4-(trifluoromethoxy)-(719277-22-2)
• EPA Substance Registry System: Benzenemethanamine, N-ethyl-4-(trifluoromethoxy)-(719277-22-2)

Safety Data

• Hazardous Substances Data: 719277-22-2(Hazardous Substances Data)

Upstream product

• 719277-21-1 N-(4-(trifluoromethoxy)benzyl)acetamide 

Relevant articles and documents

A PHARMACEUTICAL COMPOSITION COMPRISING A SUBSTITUTED PHENYLPROPIONIC ACID AS A FREE ACID AND AS TERT-BUTYL AMINE SALT THEREOF

A pharmaceutical composition comprising a compound of formula I wherein n is 1 or 2, R1 represents hydrogen, chloro, trifluoromethyl or trifluoromethoxy, R2 represents hydrogen or fluoro and R3 represents a C2-6alkyl group, wherein the compound of formula (I) is present in the composition as a free acid and as a tert-butyl amine salt thereof.

THERAPEUTIC AGENTS

The present invention provides the S enantiomer of a compound of formula (I) wherein R1 represents chloro, trifluoromethyl or trifluoromethoxy, R2 represents H or fluoro and R3 represents a C2-4alkyl group as well as pharmaceutically acceptable salts, solvates and prodrugs thereof, to processes for preparing such compounds, to their the utility in treating clinical conditions including lipid disorders (dyslipidemias) whether or not associated with insulin resistance, to methods for their therapeutic use and to pharmaceutical compositions containing them.