7195-43-9 Usage
Chemical Properties
white solid
Air & Water Reactions
Insoluble in water.
Reactivity Profile
bis(2,3-epoxypropyl) isophthalate is an ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.
Fire Hazard
Flash point data are not available for bis(2,3-epoxypropyl) isophthalate . bis(2,3-epoxypropyl) isophthalate is probably combustible.
Check Digit Verification of cas no
The CAS Registry Mumber 7195-43-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,1,9 and 5 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 7195-43:
(6*7)+(5*1)+(4*9)+(3*5)+(2*4)+(1*3)=109
109 % 10 = 9
So 7195-43-9 is a valid CAS Registry Number.
InChI:InChI=1/C14H14O6/c15-13(19-7-11-5-17-11)9-2-1-3-10(4-9)14(16)20-8-12-6-18-12/h1-4,11-12H,5-8H2
7195-43-9Relevant articles and documents
Biodegradable Poly(Amino Ester) with Aromatic Backbone as Efficient Nonviral Gene Delivery Vectors
Liu, Qiang,Su, Rong-Chuan,Yi, Wen-Jing,Zhao, Zhi-Gang
, (2017)
The development of gene delivery vectors with high efficiency and biocompatibility is one of the critical points of gene therapy. Two biodegradable poly(amino ester)s were synthesized via ring-opening polymerization between low molecular weight (LMW) PEI and diepoxide. The molecular weights of poly(amino ester)s were measured by GPC. Agarose gel retardation assays showed that these materials have good DNA-binding ability and can retard the electrophoretic mobility of plasmid DNA (pDNA) at a weight ratio of 1. The formed polyplexes have proper sizes of around 200 nm and zeta-potential values of about 30-40 mV for cellular uptake. In vitro experiments revealed that polymer P2 gave higher transfection efficiency than PEI 25KDa and Lipofectamine 2000 with less toxicity, especially in 293 cells. Results demonstrate that such a type of degradable poly(amino ester) may serve as a promising non-viral gene vector.
