71953-80-5

Basic information

• Product Name: 9ALPHA, 11, 15S-TRIHYDROXY-THROMBA-5Z, 13E, 17Z-TRIEN-1-OIC ACID
• Synonyms: 9ALPHA, 11, 15S-TRIHYDROXY-THROMBA-5Z, 13E, 17Z-TRIEN-1-OIC ACID;DELTA17-TXB2;THROMBOXANE B3;(E)-7-[4,6-dihydroxy-2-[(1E,5E)-3-hydroxyocta-1,5-dienyl]oxan-3-yl]hept-5-enoic acid;(5Z,13E,15S,17Z)-9α,11,15-Trihydroxythromboxa-5,13,17-trien-1-oic acid;TXB3;OYPPJMLKAYYWHH-NXJDUNGTSA-N
• CAS NO: 71953-80-5
• Molecular Formula: C20H32O6
• Molecular Weight: 368.46
• Mol File: 71953-80-5.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 586.1 °C at 760 mmHg
• Flash Point: 202 °C
• Appearance: /
• Density: 1.189 g/cm³
• Vapor Pressure: 3.52E-16mmHg at 25°C
• Refractive Index: 1.575
• CAS DataBase Reference: 9ALPHA, 11, 15S-TRIHYDROXY-THROMBA-5Z, 13E, 17Z-TRIEN-1-OIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 9ALPHA, 11, 15S-TRIHYDROXY-THROMBA-5Z, 13E, 17Z-TRIEN-1-OIC ACID(71953-80-5)
• EPA Substance Registry System: 9ALPHA, 11, 15S-TRIHYDROXY-THROMBA-5Z, 13E, 17Z-TRIEN-1-OIC ACID(71953-80-5)

Safety Data

• Hazardous Substances Data: 71953-80-5(Hazardous Substances Data)

Usage

Description

9ALPHA, 11, 15S-TRIHYDROXY-THROMBA-5Z, 13E, 17Z-TRIEN-1-OIC ACID, also known as Thromboxane B3 (TXB3), is the stable hydrolysis product of Thromboxane A3 (TXA3) synthesized from eicosapentaenoic acid (EPA) by cyclooxygenase (COX) and thromboxane synthase. It is biosynthesized in various tissues such as seminal vesicles, lung, polymorphonuclear leukocytes (PMNL), and ocular tissues.
Used in Pharmaceutical Industry:
9ALPHA, 11, 15S-TRIHYDROXY-THROMBA-5Z, 13E, 17Z-TRIEN-1-OIC ACID is used as a pharmaceutical agent for the treatment of various conditions related to inflammation and blood clotting. Its role in the synthesis of TXA3 and its stable nature make it a valuable compound for research and development of new therapeutic agents.
Used in Research Applications:
9ALPHA, 11, 15S-TRIHYDROXY-THROMBA-5Z, 13E, 17Z-TRIEN-1-OIC ACID is used as a research tool for studying the mechanisms of action and regulation of eicosanoids, which are important bioactive molecules involved in various physiological and pathological processes. Its presence in different tissues allows researchers to investigate its role in various diseases and conditions.
Used in Diagnostic Applications:
9ALPHA, 11, 15S-TRIHYDROXY-THROMBA-5Z, 13E, 17Z-TRIEN-1-OIC ACID can be used as a biomarker for monitoring the activity of COX and thromboxane synthase enzymes, which are involved in the synthesis of eicosanoids. Its measurement in biological samples can help in the diagnosis and assessment of various inflammatory and cardiovascular conditions.

InChI:InChI=1/C20H32O6/c1-2-3-6-9-15(21)12-13-18-16(17(22)14-20(25)26-18)10-7-4-5-8-11-19(23)24/h3-4,6-7,12-13,15-18,20-22,25H,2,5,8-11,14H2,1H3,(H,23,24)/b6-3+,7-4+,13-12+