71960-57-1Relevant articles and documents
Design and Synthesis of Highly Potent HIV-1 Protease Inhibitors Containing Tricyclic Fused Ring Systems as Novel P2 Ligands: Structure-Activity Studies, Biological and X-ray Structural Analysis
Ghosh, Arun K.,Nyalapatla, R.Prasanth,Kovela, Satish,Rao, Kalapala Venkateswara,Brindisi, Margherita,Osswald, Heather L.,Amano, Masayuki,Aoki, Manabu,Agniswamy, Johnson,Wang, Yuan-Fang,Weber, Irene T.,Mitsuya, Hiroaki
, p. 4561 - 4577 (2018/05/31)
The design, synthesis, and biological evaluation of a new class of HIV-1 protease inhibitors containing stereochemically defined fused tricyclic polyethers as the P2 ligands and a variety of sulfonamide derivatives as the P2′ ligands are described. A numb
Allenyl Allylic Ethers: Synthesis and Thermal Rearrangements
Dulcere, Jean-Pierre,Crandall, Jack,Faure, Robert,Santelli, Maurice,Agati, Valerie,Mihoubi, Mohamed N.
, p. 5702 - 5708 (2007/10/02)
Application of the sequence halogenation/dehydrohalogenation/isomerization to alkenes 1a-g affords allenyl allylic ethers 5a-g.Thermal isomerizations of 5a,d,e proceed by Claisen rearrangement, while 5b,c,f,g are transformed by alternate modes of c
A Radical Cyclisation Route to α-Methylene-γ-butyrolactones
Srikrishna, Adusumilli
, p. 587 - 588 (2007/10/02)
A three-step synthesis of α-methylene-β-butyrolactones is described, via radical cyclisation of 2-bromoalkyl prop-2-ynyl ethers (5) to 3-methylenetetrahydrofurans (6) using a tin catalyst.