71973-79-0

Basic information

• Product Name: SUC-ALA-ALA-PHE-AMC
• Synonyms: N-SUCCINYL-L-ALANYL-L-ALANYL-L-PHENYLALANINE-4-METHYL-COUMARYL-7-AMIDE;N-SUCCINYL-ALA-ALA-PHE 7-AMIDO-4-METHYLCOUMARIN;SUC-ALA-ALA-PHE-7-AMINO-4-METHYLCOUMARIN;SUC-ALA-ALA-PHE-AMC;n-succinyl-l-alanyl-l-alanyl-l-phenylalanine-4-methyl-coumaryl-7-amidefluorogenicsubstrate;Suc-AAF-AMC
• CAS NO: 71973-79-0
• Molecular Formula: C29H32N4O8
• Molecular Weight: 564.59
• Product Categories: Activity;AlphabeticalEnzyme Substrates;Fluorescent Enzyme Substrates;Fluorescent Probes, Labels, Particles and Stains;Fluorogenic
• Mol File: 71973-79-0.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 1002.6°C at 760 mmHg
• Flash Point: 560.2°C
• Appearance: /
• Density: 1.331g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.607
• Storage Temp.: −20°C
• CAS DataBase Reference: SUC-ALA-ALA-PHE-AMC(CAS DataBase Reference)
• NIST Chemistry Reference: SUC-ALA-ALA-PHE-AMC(71973-79-0)
• EPA Substance Registry System: SUC-ALA-ALA-PHE-AMC(71973-79-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26
• WGK Germany: 3
• Hazardous Substances Data: 71973-79-0(Hazardous Substances Data)

Usage

Description

SUC-ALA-ALA-PHE-AMC, also known as N-Succinyl-Ala-Ala-Phe-7-amido-4-methylcoumarin, is a fluorescently labeled tripeptide activated with succ-ester. It is commonly used in various applications across different industries due to its unique properties.

Uses

Used in Pharmaceutical Industry:
SUC-ALA-ALA-PHE-AMC is used as a substrate for enzyme assays, particularly for the detection and measurement of enzyme activity in biological samples. Its fluorescent properties allow for sensitive and accurate monitoring of enzyme activity, making it a valuable tool in drug discovery and development processes.
Used in Research and Development:
In the field of research and development, SUC-ALA-ALA-PHE-AMC serves as a valuable reagent for studying enzyme kinetics, mechanism of action, and inhibitory effects of potential drug candidates. Its ability to produce a fluorescent signal upon enzymatic cleavage enables researchers to gain insights into enzyme behavior and optimize drug design.
Used in Quality Control and Diagnostics:
SUC-ALA-ALA-PHE-AMC is employed as a quality control standard in the development and validation of diagnostic assays. Its consistent fluorescence properties ensure accurate measurement and comparison of enzyme activity levels, contributing to the reliability and reproducibility of diagnostic tests.

InChI:InChI=1/C29H32N4O8/c1-16-13-26(37)41-23-15-20(9-10-21(16)23)32-29(40)22(14-19-7-5-4-6-8-19)33-28(39)18(3)31-27(38)17(2)30-24(34)11-12-25(35)36/h4-10,13,15,17-18,22H,11-12,14H2,1-3H3,(H,30,34)(H,31,38)(H,32,40)(H,33,39)(H,35,36)