72012-83-0

Basic information

• Product Name: 1,8(2H,5H)-Acridinedione, 3,4,6,7,9,10-hexahydro-9-phenyl-
• CAS NO: 72012-83-0
• Molecular Formula: C19H19NO2
• Molecular Weight: 293.365
• Mol File: 72012-83-0.mol
• Article Data: 18

Chemical Properties

• CAS DataBase Reference: 1,8(2H,5H)-Acridinedione, 3,4,6,7,9,10-hexahydro-9-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,8(2H,5H)-Acridinedione, 3,4,6,7,9,10-hexahydro-9-phenyl-(72012-83-0)
• EPA Substance Registry System: 1,8(2H,5H)-Acridinedione, 3,4,6,7,9,10-hexahydro-9-phenyl-(72012-83-0)

Safety Data

• Hazardous Substances Data: 72012-83-0(Hazardous Substances Data)

Upstream product

• 504-02-9 1,3-cylohexanedione 
• 100-52-7 benzaldehyde 
• 5220-49-5 3-amino-cyclohex-2-enone 
• 31771-33-2 2-phenyl-4,4,6-trimethyltetrahydro-(2H)-1,3-oxazine 

Downstream Products

• 260-94-6 acridine 

Relevant articles and documents

Oxidative Fragmentation of Hydroxy Octadecadienoates Generates Biologically Active γ-Hydroxyalkenals

Oxidative fragmentation of polyunsaturated fatty acids (PUFAs) in vivo generates cytotoxic aldehydes. Among these, 4-hydroxynon-2-enal and analogous γ-hydroxyalkenal phosphatidylcholines (PCs) have attracted attention because these oxidatively truncated lipids are biologically active and have been implicated in diseases. A previous study showed that hydroxydienes, generated by allylic oxygenation of linoleic acid, are unreactive toward oxidative fragmentation. We now show that, in the presence of hydroperoxides, hydroxydienes fragment as readily as the corresponding hydroperoxydienes, generating γ-hydroxyalkenals. In a physiomimetic model study, myeloperoxidase-promoted free radical-induced fragmentation of either hydroperoxy- or hydroxyoctecadienoate esters of 2-lyso-PC in small unilamellar vesicles produced the 9-hydroxy-12-oxododec-10-enoic acid (HODA) ester HODA-PC. Therefore, hydroxydienes, that are generally more abundant in vivo than hydroperoxydienes, are plausible intermediates in the production of oxidatively truncated lipids in vivo where a constant flux of radicals and hydroperoxides is present. Our findings also show that the formation of dioxetane intermediates through peroxyradical cyclization is not required to achieve oxidative fragmentation of PUFAs.

Efficient iron catalyzed ligand-free access to acridines and acridinium ions

Acridines and acridinium ions are one of the important classes of compounds in terms of their usefulness in pharmaceuticals, materials, dyes and photo-catalysis. Here we present an unconventional FeCl3-alcohol catalysed one-pot method for their

Betainium-based ionic liquids catalyzed multicomponent Hantzsch reactions for the efficient synthesis of acridinediones

In this study, a series of betainium-based ionic liquids with various anions have been synthesized and their catalytic performances for the Hantzsch reactions have been investigated. It is shown that these ionic liquids have high selectivity for the one-p