72041-95-3

Basic information

• Product Name: 2-tert-butyl-1-(2-methylquinolin-8-yl)-3-(1,3-thiazol-2-yl)guanidine
• Synonyms: guanidine, N''-(1,1-dimethylethyl)-N-(2-methyl-8-quinolinyl)-N'-2-thiazolyl-
• CAS NO: 72041-95-3
• Molecular Formula: C₁₈H₂₁N₅S
• Molecular Weight: 339.4578
• Mol File: 72041-95-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 486.7°C at 760 mmHg
• Flash Point: 248.1°C
• Density: 1.22g/cm³
• Vapor Pressure: 1.27E-09mmHg at 25°C
• Refractive Index: 1.648
• CAS DataBase Reference: 2-tert-butyl-1-(2-methylquinolin-8-yl)-3-(1,3-thiazol-2-yl)guanidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-tert-butyl-1-(2-methylquinolin-8-yl)-3-(1,3-thiazol-2-yl)guanidine(72041-95-3)
• EPA Substance Registry System: 2-tert-butyl-1-(2-methylquinolin-8-yl)-3-(1,3-thiazol-2-yl)guanidine(72041-95-3)

Safety Data

• Hazardous Substances Data: 72041-95-3(Hazardous Substances Data)

Upstream product

• 18978-78-4 2-methyl-8-aminoquinoline 
• 72042-12-7 tert-Butyl-thiazol-2-yl-carbodiimide 

Relevant articles and documents

Basic Antiinflammatory Compounds. N,N',N''-Trisubstituted Guanidines

A variety of basic N,N',N''-trisubstituted guanidines was prepared and tested for antiinflammatory activity.Compounds with a thiazoylguanidine moiety linked to the 4 position of the 2-methylquinoline ring exhibited fairly high antiinflammatory activity.Optimal activity was associated with the presence of N-cycloalkyl substituents on N''-4-(2-methylquinolyl)-N'-2-thiazolylguanidine.Pharmalogical data on N-cyclohexyl-N''-4-(2-methylquinolyl)-N'-2-thiazolylguanidine (SR 1368, 44) are presented and discussed.