7206-76-0 Usage
Chemical Properties
White Crystalline Solid
Uses
A metabolite of Primidone
Air & Water Reactions
Insoluble in water.
Reactivity Profile
2-Ethyl-2-phenylmalonamide is an amide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).
Health Hazard
SYMPTOMS: Symptoms of exposure to a related compound through ingestion may include sedation, vertigo, dizziness, nausea, vomiting, ataxia, diplopia, nystagmus, an acute feeling of intoxication and, rarely, maculopapular and morbilliform rash, leukopenia, thrombocytopenia, systemic lupus erythematosus, lymphadenopathy, acute psychotic reactions, hemorrhagic disease in the neonate, megaloblastic anemia and osteomalacia.
Fire Hazard
Flash point data for 2-Ethyl-2-phenylmalonamide are not available. 2-Ethyl-2-phenylmalonamide is probably combustible.
Check Digit Verification of cas no
The CAS Registry Mumber 7206-76-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,2,0 and 6 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 7206-76:
(6*7)+(5*2)+(4*0)+(3*6)+(2*7)+(1*6)=90
90 % 10 = 0
So 7206-76-0 is a valid CAS Registry Number.
InChI:InChI=1/C11H14N2O2.H2O/c1-2-11(9(12)14,10(13)15)8-6-4-3-5-7-8;/h3-7H,2H2,1H3,(H2,12,14)(H2,13,15);1H2
7206-76-0Relevant articles and documents
New chemical aspects of primidone metabolism
Lafont,Cave,Menager,Miocque
, p. 61 - 66 (2007/10/02)
Primidone is metabolized either into phenylethylmalondiamide or phenobarbital. 2-Hydroxyprimidone was synthesized and tested as a potential intermediate common to these two biodegradation pathways in dogs as well as in vitro. On the other hand, the mechanism of the formation of α-phenyl-γ-butyrolactone during intoxication was investigated and the role of precursor played by the phenobarbital generated in vivo was shown.
