72105-97-6

Basic information

• Product Name: 6-methoxy-1-phenyl-1,2,3,4-tetrahydro-isoquinolin-7-ol
• Synonyms: 6-methoxy-1-phenyl-1,2,3,4-tetrahydro-isoquinolin-7-ol
• CAS NO: 72105-97-6
• Molecular Weight: 255.316
• Mol File: 72105-97-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 6-methoxy-1-phenyl-1,2,3,4-tetrahydro-isoquinolin-7-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 6-methoxy-1-phenyl-1,2,3,4-tetrahydro-isoquinolin-7-ol(72105-97-6)
• EPA Substance Registry System: 6-methoxy-1-phenyl-1,2,3,4-tetrahydro-isoquinolin-7-ol(72105-97-6)

Safety Data

• Hazardous Substances Data: 72105-97-6(Hazardous Substances Data)

Upstream product

• 1477-68-5 3-Methoxytyramine hydrochloride 
• 100-52-7 benzaldehyde 
• 554-52-9 3-Methoxytyramine 

Downstream Products

• 1032821-66-1 C₁₈H₁₉NO₃ 

Relevant articles and documents

1,2,3,4-TETRAHYDROISOQUINOLINE DERIVATIVES HAVING EFFECTS OF PREVENTING AND TREATING DEGENERATIVE AND INFLAMMATORY DISEASES

Provided are 7-hydroxy-6-methoxy-1,2,3,4-tetrahydroisoquinoline derivatives and synthesis methods thereof. The compounds significantly inhibit the production of nitrogen monoxide (NO) and superoxide in an activated microglial cell and expressions of TNF-α, IL-1β inducive NO synthase and cyclooxygenase-2 genes. They also prevent NF-kB shift to a nucleus, decrease reactive oxygen species (ROS), inhibit expression of GTP cyclohydrolase I gene and over-production of tetrahydrobiopterin (BH4), and protect dopaminergic neurons from injury due to activated microglial cells. Consequently, the compounds are effective in treating inflammatory and neurodegenerative diseases.