72143-24-9

Basic information

• Product Name: methyl 2-(propan-2-yl)pent-4-enoate
• Synonyms: 4-pentenoic acid, 2-(1-methylethyl)-, methyl ester; Methyl 2-isopropylpent-4-enoate
• CAS NO: 72143-24-9
• Molecular Formula: C₉H₁₆O₂
• Molecular Weight: 156.2221
• Mol File: 72143-24-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 160.2°C at 760 mmHg
• Flash Point: 53.1°C
• Density: 0.885g/cm³
• Vapor Pressure: 2.41mmHg at 25°C
• Refractive Index: 1.425
• CAS DataBase Reference: methyl 2-(propan-2-yl)pent-4-enoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-(propan-2-yl)pent-4-enoate(72143-24-9)
• EPA Substance Registry System: methyl 2-(propan-2-yl)pent-4-enoate(72143-24-9)

Safety Data

• Hazardous Substances Data: 72143-24-9(Hazardous Substances Data)

Upstream product

• 556-24-1 methyl 3-methylbutanoate 
• 106-95-6 allyl bromide 
• 51122-91-9 dimethyl isopropylmalonate 

Downstream Products

• 528-92-7 allylisopropylacetylurea 
• 1328885-02-4 3-allyl-5-hydroxy-3-isopropyl-1-(5-(trifluoromethyl)-2-(triisopropylsilyloxy)benzyl)pyrrolidin-2-one 
• 1328885-01-3 3-allyl-3-isopropyl-1-(5-(trifluoromethyl)-2-(triisopropylsilyloxy)benzyl)pyrrolidine-2,5-dione 
• 1328885-00-2 methyl 2-isopropyl-2-(2-oxo-2-(5-(trifluoromethyl)-2-(triisopropylsilyloxy)benzylamino)ethyl)pent-4-enoate 
• 1328884-57-6 1-(3,5-bis(trifluoromethyl)benzyl)-3-isopropyl-3-(3-(4-phenylpiperidin-1-yl)propyl)pyrrolidin-2-one trifluoroacetate 
• 1328884-95-2 3-(1-(3,5-bis(trifluoromethyl)benzyl)-3-isopropyl-2-oxopyrrolidin-3-yl)propanal 
• 1328884-94-1 1-(3,5-bis(trifluoromethyl)benzyl)-3-(3-hydroxypropyl)-3-isopropylpyrrolidin-2-one 
• 1328884-51-0 1-(3,5-bis(trifluoromethyl)benzyl)-3-isopropyl-3-(2-(piperidin-1-yl)ethyl)pyrrolidin-2-one trifluoroacetate 
• 1328884-93-0 2-(1-(3,5-bis(trifluoromethyl)benzyl)-3-isopropyl-2-oxopyrrolidin-3-yl)acetaldehyde 
• 1328884-88-3 3-allyl-1-(3,5-bis(trifluoromethyl)benzyl)-3-isopropylpyrrolidin-2-one 
• 1328884-92-9 C₁₉H₁₉F₆NO 
• 1328884-91-8 C₂₀H₂₃F₆NO₂ 

Relevant articles and documents

METHOD FOR PREPARING APRONAL AND INTERMEDIATE THEREOF

PROBLEM TO BE SOLVED: To provide a simple, cost-effective and improved method for synthesizing apronal and an intermediate alkyl 2-isopropyl-4-pentenoate used in the synthesis of allylisopropylacetylurea of apronal. SOLUTION: There is provided a method including a step of reacting an alkyl 2-isopropyl-4-pentenoate with an alkali metal salt such as sodium urea in the presence of an aprotic polar solvent or a mixture of solvents to obtain apronal of the following formula (1). In addition, the present invention also includes a method for preparing the intermediate alkyl 2-isopropyl-4-pentenoate by dealkoxycarbonylation of dialkylallyl isopropyl malonate. SELECTED DRAWING: None COPYRIGHT: (C)2020,JPOandINPIT

Diastereoselective access to trans -2-substituted cyclopentylamines

A highly diastereoselective synthesis of trans-2-substituted cyclopentylamines via a tandem hydrozirconation/Lewis acid-mediated cyclization sequence applied to butenyl oxazolidines is described. The method allows an easy preparation of diversely substituted cyclopentylamines which appear to be useful synthetic intermediates. This was further illustrated by the syntheses of (±)-Rodocaine, (±)-trans-pentacin, and enantiomerically enriched trans-cyclopentane-1,2-diamine.