72195-25-6

Basic information

• Product Name: Quinoline, 2-(2-methoxyphenyl)-
• CAS NO: 72195-25-6
• Molecular Formula: C16H13NO
• Molecular Weight: 235.285
• Mol File: 72195-25-6.mol
• Article Data: 38

Chemical Properties

• CAS DataBase Reference: Quinoline, 2-(2-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Quinoline, 2-(2-methoxyphenyl)-(72195-25-6)
• EPA Substance Registry System: Quinoline, 2-(2-methoxyphenyl)-(72195-25-6)

Safety Data

• Hazardous Substances Data: 72195-25-6(Hazardous Substances Data)

Upstream product

• 91-22-5 quinoline 
• 56772-78-2 1-(2,2-dichlorovinyl)-2-methoxybenzene 
• 5720-06-9 2-Methoxyphenylboronic acid 
• 5344-90-1 2-Aminobenzyl alcohol 
• 13513-82-1 1-(2-methoxyphenyl)ethanol 
• 1504-61-6 2-methoxycinnamyl alcohol 
• 62-53-3 aniline 
• 1309371-20-7 (E)-1-(2-methoxyphenyl)-3-(2-nitrophenyl)prop-2-en-1-one 
• 552-89-6 2-nitro-benzaldehyde 
• 579-74-8 2-Methoxyacetophenone 
• 612-25-9 2-Nitrobenzyl alcohol 
• 4403-69-4 2-amino-1-benzylamine 
• 612-62-4 2-Chloroquinoline 
• 16750-63-3 2-methoxyphenylmagnesium bromide 

Downstream Products

• 1242160-43-5 C₁₆H₁₇NO 
• 612-96-4 2-Phenylquinoline 
• 1198359-55-5 (R)-2-(2-methoxyphenyl)-1,2,3,4-tetrahydroquinoline 
• 1198359-74-8 2-(2-methoxyphenyl)quinoline hydrobromide 
• 178990-29-9 4-chloro-2-(2-methoxy-phenyl)-quinoline 
• 112752-09-7 2-(2-hydroxy-5-nitrophenyl)-quinoline 
• 42731-96-4 2-quinolin-2-yl-phenol 
• 72195-24-5 2-(2-methoxyphenyl)quinoline 1-oxide 

Relevant articles and documents

Nickel-catalyzed α-alkylation of ketones with benzyl alcohols

We reported an efficient method for α-alkylation of ketones with benzyl alcohols using the pyridine-bridged pincer-type N-heterocyclic carbenes nickel complexes as catalysts. A wide range of ketones and benzyl alcohols were efficiently converted into various alkylated products in moderate to high yields. In addition, these nickel complexes were also successfully applied for the synthesis of a wide range of quinoline derivatives.

The preparation of a Co@C3N4catalyst and applications in the synthesis of quinolines from 2-aminobenzyl alcohols with ketones

An unsymmetrical diphenylphosphino-pyridinyl-triazole ligand was synthesized and characterized through IR, NMR and MS and the corresponding earth-abundant metal complex (cobalt) was prepared. Considering energy consumption and environmental friendliness, it is necessary to turn this diphenylphosphino-pyridinyl-triazole cobalt complex into a recyclable catalyst, which could easily be reused. Therefore, a heterogeneous catalyst was synthesized through Co-doping of C3N4, and the Co-nanoparticles on C3N4revealed high catalytic activity for the synthesis of quinolines with good recovery performance.

Organometal-Free Arylation and Arylation/Trifluoroacetylation of Quinolines by Their Reaction with CF3-ynones and Base-Induced Rearrangement

The reaction of quinolines with CF3-ynones resulted in the formation of 1,3-oxazinoquinolines. Subsequent treatment of the reaction mixture with a base initiated deep structural transformation of primary products. Both steps proceed in very high yield. As a result, unusual rearrangement of 1,3-oxazinoquinolines to form either 2-arylquinolines or 2-aryl-3-trifluoroacetylquinolines was discovered. The decisive role of the base in the reaction direction was shown. Using these reactions, highly efficient pathways to 2-arylquinolines and 2-aryl-3-trifluoroacetylquinolines were elaborated to provide the corresponding compounds in high yields using a simple one-pot procedure. The possible mechanism of rearrangement is discussed.