721970-35-0

Basic information

• Product Name: Methyl 1-cyclopropyl-6-fluoro-7-(hexahydro-1H-pyrrolo [3, 4-b]pyridin-6(2H)-yl)-8-Methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylate
• Synonyms: Methyl 1-cyclopropyl-6-fluoro-7-(hexahydro-1H-pyrrolo [3, 4-b]pyridin-6(2H)-yl)-8-Methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylate;1-Cyclopropyl-6-fluoro-1,4-dihydro-8-Methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylic Acid Methyl Ester;Moxifloxacin Methyl Ester;Moxifloxacin Impurity F (Moxifloxacin Methyl Ester)
• CAS NO: 721970-35-0
• Molecular Formula: C₂₂H₂₆FN₃O₄
• Molecular Weight: 415.4579432
• Product Categories: Aromatics;Heterocycles;Impurities;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 721970-35-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 609.1±55.0 °C(Predicted)
• Appearance: /
• Density: 1.338±0.06 g/cm3(Predicted)
• Storage Temp.: -20°C Freezer
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• PKA: 10.58±0.20(Predicted)
• CAS DataBase Reference: Methyl 1-cyclopropyl-6-fluoro-7-(hexahydro-1H-pyrrolo [3, 4-b]pyridin-6(2H)-yl)-8-Methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 1-cyclopropyl-6-fluoro-7-(hexahydro-1H-pyrrolo [3, 4-b]pyridin-6(2H)-yl)-8-Methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylate(721970-35-0)
• EPA Substance Registry System: Methyl 1-cyclopropyl-6-fluoro-7-(hexahydro-1H-pyrrolo [3, 4-b]pyridin-6(2H)-yl)-8-Methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylate(721970-35-0)

Safety Data

• Hazardous Substances Data: 721970-35-0(Hazardous Substances Data)

Usage

Uses

Moxifloxacin Methyl Ester is an impurity of the antibacterial Moxifloxacin (M745020).

Upstream product

• 141290-02-0 1-cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinoline carboxylic acid methyl ester 
• 151213-40-0 (1S,6S)-2,8-diazabicyclo[4.3.0]nonane 
• 67-56-1 methanol 
• 151096-09-2 moxifloxacin 

Relevant articles and documents

New moxifloxacin impurity and preparation method and use thereof

The invention provides a new moxifloxacin impurity and provides a preparation method and use as an impurity control of the new impurity. A commercially available bulk simple chemical is used as a starting material to construct a chiral dual ring, and further an impurity compound is synthesized; the reaction process has no need of chiral resolution; in addition, the operation is simple, the reaction condition is mild, and the application prospect is good. The moxifloxacin prepared by the invention has high impurity purity, and effectively ensures the purity of the impurity control and the accuracy of analysis work.

Phosphonated Fluoroquinolones, Antibacterial Analogs Thereof, and Methods for the Prevention and Treatment of Bone and Joint Infections

The present invention relates to phosphonated fluoroquinolones, antibacterial analogs thereof, and methods of using such compounds. These compounds are useful as antibiotics for prevention and/or the treatment of bone and joint infections, especially for the prevention and/or treatment of osteomyelitis.