72299-62-8 Usage
General Description
7-Iodo-1,2,3,4-tetrahydroisoquinoline is a chemical compound with the molecular formula C9H10INO. It is a derivative of tetrahydroisoquinoline, a heterocyclic compound found in a variety of natural products and pharmaceuticals. The addition of an iodo group to the tetrahydroisoquinoline molecule imparts a unique reactivity and potential for use in chemical synthesis and drug discovery. 7-Iodo-1,2,3,4-tetrahydroisoquinoline has been studied for its potential as a building block in organic synthesis and for its pharmacological properties. Its structure and reactivity make it an interesting target for further research in the fields of medicinal chemistry and chemical synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 72299-62-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,2,9 and 9 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 72299-62:
(7*7)+(6*2)+(5*2)+(4*9)+(3*9)+(2*6)+(1*2)=148
148 % 10 = 8
So 72299-62-8 is a valid CAS Registry Number.
72299-62-8Relevant articles and documents
Synthesis, biochemical evaluation, and classical and three-dimensional quantitative structure-activity relationship studies of 7-substituted- 1,2,3,4-tetrahydroisoquinolines and their relative affinities toward phenylethanolamine N-methyltransferase and t
Grunewald, Gary L.,Dahanukar, Vilas H.,Jalluri, Ravi K.,Criscione, Kevin R.
, p. 118 - 134 (2007/10/03)
7-Substituted-1,2,3,4-tetrahydroisoquinolines (7-substituted-THIQs) are potent inhibitors of phenylethanolamine N-methyltransferase (PNMT, EC 2.1.1.28), the enzyme involved in the biosynthesis of epinephrine. Unfortunately, most of these compounds also ex