72300-69-7 Usage
Description
(R)-C-PYRROLIDIN-2-YL-METHYLAMINE, also known as (R)-Pyrrolidin-2-ylmethanamine, is an organic compound that serves as a crucial intermediate in the synthesis of various pharmaceuticals. It is characterized by its unique molecular structure, which includes a pyrrolidine ring and a methylamine functional group. (R)-C-PYRROLIDIN-2-YL-METHYLAMINE plays a significant role in the development of new antitumor agents, particularly in the synthesis of Miboplatin (M342100), a platinum coordination complex.
Uses
Used in Pharmaceutical Industry:
(R)-C-PYRROLIDIN-2-YL-METHYLAMINE is used as a key intermediate in the synthesis of Miboplatin (M342100) for its role in developing new antitumor agents. Miboplatin is a platinum coordination complex that has been identified and developed in Japan as a promising treatment option for various types of cancer. (R)-C-PYRROLIDIN-2-YL-METHYLAMINE's unique structure allows it to form stable complexes with platinum, which are known for their potent antitumor activity.
In the development of Miboplatin, (R)-C-PYRROLIDIN-2-YL-METHYLAMINE contributes to the compound's ability to target and damage cancer cells, ultimately leading to their destruction. This makes it a valuable component in the fight against cancer and a critical element in the ongoing research and development of novel antitumor agents.
Furthermore, the compound's versatility in chemical reactions and its compatibility with various functional groups make it a potential candidate for use in other pharmaceutical applications, such as the synthesis of other therapeutic agents or the development of drug delivery systems. As research continues, it is possible that (R)-C-PYRROLIDIN-2-YL-METHYLAMINE will be utilized in a broader range of applications within the pharmaceutical industry, further expanding its importance in the development of new treatments for various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 72300-69-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,3,0 and 0 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 72300-69:
(7*7)+(6*2)+(5*3)+(4*0)+(3*0)+(2*6)+(1*9)=97
97 % 10 = 7
So 72300-69-7 is a valid CAS Registry Number.
InChI:InChI=1/C5H12N2/c6-4-5-2-1-3-7-5/h5,7H,1-4,6H2/t5-/m1/s1
72300-69-7Relevant articles and documents
Enantioselective Synthesis of 2-Aminomethyl and 3-Amino Pyrrolidines and Piperidines through 1,2-Diamination of Aldehydes
Ansari, Anas,Ramapanicker, Ramesh
, p. 8161 - 8169 (2018/07/25)
An efficient method for the synthesis of 1,2-diamines from aldehydes through proline-catalyzed asymmetric α-amination followed by reductive amination is reported. The products resemble those obtained through direct asymmetric diamination of terminal alkenes. The methodology is used to synthesize 2-aminomethyl and 3-amino pyrrolidines and piperidines in high yields and with a good enantioselectivity. The usefulness of the method is demonstrated through the synthesis of a 2-aminomethyl iminocyclitol.
Biomimetic asymmetric aldol reactions catalyzed by proline derivatives attached to β-cyclodextrin in water
Shen, Hai-Min,Ji, Hong-Bing
supporting information; experimental part, p. 3541 - 3545 (2012/09/08)
Two proline derivatives, (S)-2-aminomethylpyrrolidine and (R)-2-aminomethylpyrrolidine modified β-CD (CD-1, CD-2) were synthesized in the yields of 31% and 14%. Their self-inclusion conformations were characterized by 1H ROESY NMR studies and q
CHEMICAL COMPOUNDS
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Page/Page column 81-82, (2008/06/13)
The present invention relates generally to novel therapeutic compounds and AXOR 109 agonists, and processes for the manufacture and use of the same.
