723284-41-1

Basic information

• Product Name: C₂₀H₁₄FNO₂
• Synonyms: C₂₀H₁₄FNO₂
• CAS NO: 723284-41-1
• Molecular Weight: 319.335
• Mol File: 723284-41-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₀H₁₄FNO₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₀H₁₄FNO₂(723284-41-1)
• EPA Substance Registry System: C₂₀H₁₄FNO₂(723284-41-1)

Safety Data

• Hazardous Substances Data: 723284-41-1(Hazardous Substances Data)

Upstream product

• 86-79-3 2-hydroxycarbazole 
• 403-29-2 2-bromo-4'-fluoroacetophenone 

Downstream Products

• 1031512-95-4 2-(9H-carbazol-2-yloxy)-N-(4-fluorophenyl)acetamide 

Relevant articles and documents

Synthesis and antiproliferative evaluation of amide-containing anthraquinone, xanthone, and carbazole

Certain amide-containing anthraquinone, xanthone, and carbazole derivatives have been synthesized and evaluated in vitro for their antiproliferative activities against a panel of human cancer cell lines including nasopharyngeal carcinoma (NPC-TW01), lung carcinoma (NCI-H661), and leukemia (Jurkat). Among them, 2-(9,10-dioxo-9,10-dihydroanthracen-2-yloxy)-N-(naphthalen-2-yl)acetamide (13) was the most active against NPC-TW01 with an IC50 value of 2.62 μM while its xanthone and dibenzofuran counterparts, 14 and 15, were inactive with an IC50 value of 16.10 and 11.09 μM, respectively. Studies on NPC-TW01 cell cycle distribution revealed that compound 13 inhibited proliferation of NPC-TW01 by the alteration of cell division and the accumulation of cells in G0/G1 phase.