72368-50-4Relevant articles and documents
Chemoselective Schwartz Reagent Mediated Reduction of Isocyanates to Formamides
Pace, Vittorio,De La Vega-Hernández, Karen,Urban, Ernst,Langer, Thierry
supporting information, p. 2750 - 2753 (2016/06/15)
Addition of the in situ generated Schwartz reagent to widely available isocyanates constitutes a chemoselective, high-yielding, and versatile approach to the synthesis of variously functionalized formamides. Steric and electronic factors or the presence of sensitive functionalities (esters, nitro groups, nitriles, alkenes) do not compromise the potential of the method. Full preservation of the stereochemical information contained in the starting materials is observed. The use of formamides in the nucleophilic addition of organometallic reagents (Chida-Sato allylation, Charette-Huang addition to imidoyl triflate activated amides, Matteson homologation of boronic esters) is briefly investigated.
A simple method for preparation of ZnO nanoparticles as a highly efficient nanocatalyst for N-formylation of primary and secondary amines under solvent-free condition
Alinezhad, Heshmatollah,Salehian, Fatemeh
, p. 532 - 538 (2013/07/19)
A convenient reaction between alky, aryl, and heteroalkyl amines and formic acid as a formylating agent in the presence of catalytic amount of mechanochemically synthesized zinc oxide nanoparticles under solvent-free condition for the synthesis of corresponding N-formyl derivatives is described. Copyright Taylor and Francis Group, LLC.
Synthesis of 4-hydroxy-3-quinolinecarboxylic acid derivatives by a condensation/cyclization sequence between o-isocyanobenzoates and magnesium enolates
Kobayashi, Kazuhiro,Nakashima, Toshio,Mano, Masaaki,Morikawa, Osamu,Konishi, Hisatoshi
, p. 602 - 603 (2007/10/03)
Addition of magnesium ester and amide enolates, generated using an excess amount of a magnesium amide (from diisopropylamine and ethylmagnesium bromide), to o-isocyanobenzoates affords 4-hydroxy-3-quinolinecarboxylic esters and amides by a tandem Claisen-type condensation/cyclization sequence.
