72404-28-5

Basic information

• Product Name: 2H-1-Benzopyran-2-one, 7-(diethylamino)-3-(4-phenyl-2-thiazolyl)-
• CAS NO: 72404-28-5
• Molecular Formula: C22H20N2O2S
• Molecular Weight: 376.479
• Mol File: 72404-28-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2H-1-Benzopyran-2-one, 7-(diethylamino)-3-(4-phenyl-2-thiazolyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-1-Benzopyran-2-one, 7-(diethylamino)-3-(4-phenyl-2-thiazolyl)-(72404-28-5)
• EPA Substance Registry System: 2H-1-Benzopyran-2-one, 7-(diethylamino)-3-(4-phenyl-2-thiazolyl)-(72404-28-5)

Safety Data

• Hazardous Substances Data: 72404-28-5(Hazardous Substances Data)

Upstream product

• 23764-68-3 5-Diethylamino-2-{[(E)-4-nitro-phenylimino]-methyl}-phenol 
• 41381-89-9 2-(4-phenylthiazol-2-yl)acetonitrile 
• 70-11-1 α-bromoacetophenone 
• 72404-46-7 Diethyl-[2-imino-3-(4-phenyl-thiazol-2-yl)-2H-chromen-7-yl]-amine 
• 91-68-9 3-diethylaminophenol 
• 21260-38-8 7-(diethylamino)-2-oxo-2H-chromene-3-carboxamide 
• 28705-46-6 ethyl 7-diethylaminocoumarin-3-carboxylate 
• 72410-22-1 7-diethylamino-2-oxo-2H-chromene-3-carbothioic acid amide 

Relevant articles and documents

DERIVATIVES OF CHROMEN-2-ONE AS INHIBITORS OF VEGF PRODUCTION IN MAMMALIAN CELLS

The compounds of formula (I) wherein A and R1-R5 are as defined in the description, are inhibitors of Vascular Endothelial Growth Factor and are useful as angiogenesis inhibitors and antiproliferative agents.

A Simple Route to N(2'-Hydroxy)-arylidene-nitroanilines-Versatile Synthones for Coumarines

In a three-component reaction with ortho formic esters and nitroaniline activated phenols are easily transferred to N(2'-hydroxy)-arylidene-nitroanilines.The reaction is commonly applicable and gives the N(2'-hydroxy-4'-N,N-dialkylamino)-benzylidene-nitroanilines 10 in good yields also with the air-unstable m-N,N-dialkylaminophenols 8.The prepared 2-hydroxy-azomethines are convertable into boroncomplexes 14 and coumarine derivatives 17, respectively.