72473-04-2

Basic information

• Product Name: 1-(3-hydroxypropyl)-2-(2-methoxy-6-methylbenzoyl)methylpyrrolidine
• Synonyms: 1-(3-hydroxypropyl)-2-(2-methoxy-6-methylbenzoyl)methylpyrrolidine
• CAS NO: 72473-04-2
• Molecular Weight: 291.39
• Mol File: 72473-04-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(3-hydroxypropyl)-2-(2-methoxy-6-methylbenzoyl)methylpyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-hydroxypropyl)-2-(2-methoxy-6-methylbenzoyl)methylpyrrolidine(72473-04-2)
• EPA Substance Registry System: 1-(3-hydroxypropyl)-2-(2-methoxy-6-methylbenzoyl)methylpyrrolidine(72473-04-2)

Safety Data

• Hazardous Substances Data: 72473-04-2(Hazardous Substances Data)

Upstream product

• 155106-27-7 (E)-1-(3-hydroxypropyl)-2-(2-methoxy-6-methylbenzoyl)methylenepyrrolidine 
• 155106-26-6 (E)-1-(3-acetoxypropyl)-2-(2-methoxy-6-methylbenzoyl)methylenepyrrolidine 
• 62012-15-1 1-(3-hydroxypropyl)pyrrolidin-2-one 
• 62012-14-0 1-(3-acetoxypropyl)pyrrolidin-2-one 
• 155106-23-3 3-(2-thioxo-1-pyrrolidinyl)propyl acetate 

Relevant articles and documents

Formal synthesis of two Elaeocarpus alkaloids: elaeocarpine and isoelaeocarpine

1-(3-Acetoxypropyl)pyrrolidine-2-thione 7, prepared by acetylation and thionation of the readily accessible 1-(3-hydroxypropyl)pyrrolidin-2-one 5, undergoes Eschenmoser alkylidenation (sulfide contraction) with two phenacyl bromides to give the vinylogous amides (E)-1-(3-acetoxypropyl)-2-benzoylmethylenepyrrolidine 8 and the corresponding 2-methoxy-6-methylbenzoyl analogue 14.Reduction of the latter with lithium aluminium hydride yields 1-(3-hydroxypropyl)-2-(2-methoxy-6-methylbenzoyl)methylpyrrolidine 12, thereby completing a formal synthesis of the Elaeocarpus alkaloids elaeocarpine 10 and isoelaeocarpine 11.