724788-64-1

Basic information

• Product Name: ethyl 4-broMo-6-Methoxy-1,5-naphthyridine-3-carboxylate
• Synonyms: ethyl 4-broMo-6-Methoxy-1,5-naphthyridine-3-carboxylate;4-BroMo-6-Methoxy-[1,5]naphthyridine-3-carboxylic acid ethyl ester
• CAS NO: 724788-64-1
• Molecular Formula: C₁₂H₁₁BrN₂O₃
• Molecular Weight: 311.13134
• Mol File: 724788-64-1.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 381.5±37.0 °C(Predicted)
• Appearance: /
• Density: 1.520±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 0.23±0.10(Predicted)
• CAS DataBase Reference: ethyl 4-broMo-6-Methoxy-1,5-naphthyridine-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 4-broMo-6-Methoxy-1,5-naphthyridine-3-carboxylate(724788-64-1)
• EPA Substance Registry System: ethyl 4-broMo-6-Methoxy-1,5-naphthyridine-3-carboxylate(724788-64-1)

Safety Data

• Hazardous Substances Data: 724788-64-1(Hazardous Substances Data)

Usage

General Description

Ethyl 4-bromo-6-methoxy-1,5-naphthyridine-3-carboxylate is a chemical compound with the molecular formula C14H12BrNO4. It is a derivative of naphthyridine, containing a bromine atom, a methoxy group, and an ethyl ester. ethyl 4-broMo-6-Methoxy-1,5-naphthyridine-3-carboxylate has potential applications in the field of organic synthesis or medicinal chemistry, as it may possess pharmacological properties or be useful in the development of new drugs. However, it is important to handle this chemical with caution, as it may present hazards if not properly handled or disposed of. Further research and testing are necessary to fully understand the potential uses and risks associated with ethyl 4-bromo-6-methoxy-1,5-naphthyridine-3-carboxylate.

Upstream product

• 13049-86-0 diethyl 2-(ethoxycarbonylmethylene)malonate 
• 87-13-8 diethyl 2-ethoxymethylenemalonate 
• 6628-77-9 6-methoxy-pyridin-3-ylamine 
• 53241-92-2 4-Hydroxy-6-methoxy-[1,5]naphthyridine-3-carboxylic Acid Ethyl Ester 
• 53241-90-0 diethyl {[(6-methoxypyridin-3-yl)amino]methylidene}propanedioate 
• 724788-63-0 ethyl 6-methoxy-4-oxo-1,4-dihydro-1,5-naphthyridine-3-carboxylate 

Downstream Products

• 724788-65-2 4-bromo-6-methoxy-1,5-naphthyridine-3-carboxylic acid 
• 724788-66-3 4-bromo-6-(methyloxy)-1,5-naphthyridin-3-amine 
• 724788-70-9 8-bromo-7-fluoro-2-methoxy-1,5-naphthyridine 
• 1417551-48-4 t-butyl 4-bromo-6-methoxy-1,5-naphthyridine-3-yl-carbamate 
• 1415415-01-8 7-fluoro-2-methoxy-8-methyl-1,5-naphthyridine 
• 1616409-89-2 t-butyl 1-(2-(3-fluoro-6-methoxy-1,5-naphthyridin-4-yl)-1-hydroxyethyl)-2-oxabicyclo[2.2.2]octan-4-ylcarbamate 
• 1616409-88-1 t-butyl 1-(2-(3-fluoro-6-methoxy-1,5-naphthyridin-4-yl)-1-hydroxyethyl)-2-oxabicyclo[2.2.2]octan-4-ylcarbamate 
• 1375745-09-7 C₃₉H₃₆BBrF₃N₅O₃ 
• 1375745-10-0 C₄₇H₄₆BF₃N₆O₃ 
• 1375745-06-4 ethyl 4-(2-fluoro-4-formylphenyl)-6-methoxy-1,5-naphthyridine-3-carboxylate 
• 1310359-71-7 ethyl 4-(2-chloro-4-methylphenyl)-6-methoxy-1,5-naphthyridine-3-carboxylate 
• 1310359-68-2 ethyl 4-(2,3-dichlorophenyl)-6-methoxy-1,5-naphthyridine-3-carboxylate 
• 1310359-80-8 ethyl 4-(2,3-dichlorophenyl)-6-oxo-5,6-dihydro-1,5-naphthyridine-3-carboxylate 
• 1310359-72-8 ethyl 4-(2-chloro-4-methoxyphenyl)-6-methoxy-1,5-naphthyridine-3-carboxylate 

Relevant articles and documents

ANTIBACTERIAL COMPOUNDS HAVING BROAD SPECTRUM OF ACTIVITY

The present invention relates to novel antibacterial compounds, pharmaceutical compositions containing them and their use as antimicrobials.

Novel amino-piperidines as potent antibacterials targeting bacterial type IIA topoisomerases

We have identified a series of amino-piperidine antibacterials with a good broad spectrum potency. We report the investigation of various subunits in this series and advanced studies on compound 8. Compound 8 possesses good pharmacokinetics, broad spectrum antibacterial activity and demonstrates oral efficacy in a rat lung infection model.

ANTIBACTERIAL AGENTS

Naphthalene, quinoline, quinoxaline and naphthyridine derivatives useful in the treatment of bacterial infections in mammals, particularly humans, are disclosed herein.