7249-30-1 Usage
Functional Groups
Chloro-substituted phenyl group
Two amino groups on the pyrimidine ring
Potential Applications
Pharmaceutical industry: Development of new drugs
Research reagent: Biochemical studies
Versatility
Presence of chloro and amino groups enables synthesis of various derivatives
Biological Activities
Potential for derivatives with valuable biological activities.
Check Digit Verification of cas no
The CAS Registry Mumber 7249-30-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,2,4 and 9 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 7249-30:
(6*7)+(5*2)+(4*4)+(3*9)+(2*3)+(1*0)=101
101 % 10 = 1
So 7249-30-1 is a valid CAS Registry Number.
7249-30-1Relevant articles and documents
Design and synthesis of novel antibacterial agents with inhibitory activity against DNA polymerase III
Ali, Amjad,Aster, Susan D.,Graham, Donald W.,Patel, Gool F.,Taylor, Gayle E.,Tolman, Richard L.,Painter, Ronald E.,Silver, Lynn L.,Young, Katherine,Ellsworth, Kenneth,Geissler, Wayne,Harris, Georgianna S.
, p. 2185 - 2188 (2007/10/03)
4-Substituted 2-amino-6-(anilino)pyrimidines have been found to be selective inhibitors of DNA polymerase III, a replicative enzyme known to be essential in the DNA synthesis of Gram-positive bacteria. Among the analogues, 18 displayed an IC50 of 10 μM against DNA polymerase III from Staphylococcus aureus.
