7250-43-3

Basic information

• Product Name: N,N'-Ethylenebis(iodoacetamide)
• Synonyms: N,N'-Ethylenebis(2-iodoacetamide);S-25;Acetamide, N,N'-1,2-ethanediylbis[2-iodo-;Acetamide, N,N'-ethylenebis[2-iodo-;Acetamide, N,N'-ethylenebis[iodo-;Ethylenediamine bis(iodoacetamide);Nsc30028;S 35
• CAS NO: 7250-43-3
• Molecular Formula: C6H10I2N2O2
• Molecular Weight: 0
• Product Categories: Cross Linking Reagents;Aliphatics;MTS & Sulfhydryl Active Reagents
• Mol File: 7250-43-3.mol
• Article Data: 0

Chemical Properties

• Melting Point: 214°C
• Appearance: /
• Storage Temp.: Amber Vial, -20°C Freezer
• Stability: Sensitive to Light; Sensitive to Temperature
• CAS DataBase Reference: N,N'-Ethylenebis(iodoacetamide)(CAS DataBase Reference)
• NIST Chemistry Reference: N,N'-Ethylenebis(iodoacetamide)(7250-43-3)
• EPA Substance Registry System: N,N'-Ethylenebis(iodoacetamide)(7250-43-3)

Safety Data

• Hazardous Substances Data: 7250-43-3(Hazardous Substances Data)

Usage

Description

N,N'-Ethylenebis(iodoacetamide) is a white crystalline solid that is known for its specific reactivity with the sulfhydryl groups in tubulin molecules. This characteristic makes it a valuable tool for studying the conformational state of tubulin, a protein that plays a crucial role in cell division and intracellular transport.

Uses

Used in Biochemical Research:
N,N'-Ethylenebis(iodoacetamide) is used as a probe for the conformational state of the tubulin molecule. It reacts specifically with the sulfhydryl groups in tubulin, allowing researchers to gain insights into the structure and function of this important protein. This application is particularly relevant in the fields of cell biology and molecular biology, where understanding the dynamics of tubulin is essential for advancing our knowledge of cellular processes.