726138-31-4

Basic information

• Product Name: 2-Amino-3,5-diphenylpyridine
• Synonyms: 2-Amino-3,5-diphenylpyridine
• CAS NO: 726138-31-4
• Molecular Formula: C₁₇H₁₄N₂
• Molecular Weight: 246.31
• Mol File: 726138-31-4.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Amino-3,5-diphenylpyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-3,5-diphenylpyridine(726138-31-4)
• EPA Substance Registry System: 2-Amino-3,5-diphenylpyridine(726138-31-4)

Safety Data

• Hazardous Substances Data: 726138-31-4(Hazardous Substances Data)

Usage

Applications

Used in organic chemistry as a building block for:
Synthesis of pharmaceuticals
Synthesis of agrochemicals
Synthesis of dyes
Studied for potential pharmacological properties including:
Anti-cancer effects
Anti-inflammatory effects

Biological Activities

Investigated for potential pharmacological properties
Potential anti-cancer and anti-inflammatory effects

Industrial Applications

Valuable intermediate in organic synthesis
Utilized in various industries

Upstream product

• 35486-42-1 2-amino-3,5-dibromopyridine 
• 98-80-6 phenylboronic acid 
• 504-29-0 2-aminopyridine 
• 13965-03-2 bis-triphenylphosphine-palladium(II) chloride 
• 497-19-8 sodium carbonate 

Downstream Products

• 726138-30-3 2-(4-bromo-phenyl)-6,8-diphenyl-imidazo[1,2-a]pyridine 
• 873913-89-4 [3-(3,5-diphenyl-pyridin-2-yl)-prop-2-ynyl]-dimethyl-amine 
• 873913-82-7 2-iodo-3,5-diphenylpyridine 

Relevant articles and documents

Synthesis and evaluation of the anticoccidial activity of trifluoropyrido[1,2-a]pyrimidin-2-one derivatives

Screening of our chemical library to discover new molecules exhibiting in vitro activity against the invasion of host cells by Eimeria tenella revealed a lead compound with an IC50 of 15 μM. Structure-activity relationship studies were conducted with 34 newly synthesized compounds to identify more active molecules and enhance in vitro activity against the parasite. Four compounds were more effective in inhibiting MDBK cell invasion in vitro than the lead compound.

AMIDE COMPOUND

The present invention relate to a compound represented by the formula (I) or (II) wherein ring A is an optionally substituted ring (the ring should not be pyrrolidine, piperidine and piperazine), ring B is an optionally substituted aromatic ring, ring D is an optionally substituted ring, R1 and R2 are each independently a hydrogen atom or a substituent, R3 is a hydrogen atom or a C1-6 alkyl group, or R3 is bonded to ring A to form a non-aromatic ring, ring Aa is an optionally substituted aromatic hydrocarbon, Y is CH or N, Ra1 is an optionally substituted hydrocarbon group, and Ra2 and Ra3 are each independently a hydrogen atom or a substituent, or a salt thereof. The present invention provides a compound having a DGAT inhibitory activity, which is useful for the treatment or amelioration of diseases or pathologies caused by high expression or high activation of DGAT.

New calcineurin inhibiting 3-dimethylaminopropyl substituted diarylheterocycles by sonogashira reactions and catalytic hydrogenation

A series of calcineurin inhibiting compounds 1 consisting of a central aromatic N-heterocycle, two aryl substituents and a 3-dimethylaminopropyl chain was synthesized by introduction of the side chain. A corresponding haloheterocycle 3 was transformed int