72630-78-5 Usage
Description
5-Chloro-2,4-difluoro-6-methyl-pyrimidine, with the CAS number 72630-78-5, is an organic compound that serves as a valuable building block in the field of organic synthesis. It is characterized by its unique molecular structure, which features a pyrimidine ring with a chlorine atom at the 5th position, two fluorine atoms at the 2nd and 4th positions, and a methyl group at the 6th position. 5-CHLORO-2,4-DIFLUORO-6-METHYL-PYRIMIDINE's distinct structural features make it a versatile and promising intermediate for the development of various pharmaceuticals, agrochemicals, and other specialty chemicals.
Uses
Used in Pharmaceutical Industry:
5-Chloro-2,4-difluoro-6-methyl-pyrimidine is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structural features allow for the development of new drugs with improved efficacy, selectivity, and reduced side effects. 5-CHLORO-2,4-DIFLUORO-6-METHYL-PYRIMIDINE's reactivity and functional group compatibility make it an attractive candidate for the design and synthesis of novel therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical industry, 5-chloro-2,4-difluoro-6-methyl-pyrimidine is utilized as a starting material for the development of new pesticides, herbicides, and insecticides. Its structural diversity and compatibility with various functional groups enable the creation of innovative agrochemicals with enhanced performance, selectivity, and environmental compatibility.
Used in Organic Synthesis:
5-Chloro-2,4-difluoro-6-methyl-pyrimidine is employed as a versatile building block in organic synthesis, allowing for the construction of a wide range of complex organic molecules. Its unique structural features and reactivity make it an ideal candidate for the synthesis of various specialty chemicals, including dyes, polymers, and advanced materials.
Used in Research and Development:
5-CHLORO-2,4-DIFLUORO-6-METHYL-PYRIMIDINE is also used in research and development settings, where it serves as a valuable tool for understanding the structure-activity relationships of various biologically active molecules. Its unique structural features and reactivity enable researchers to explore new synthetic routes and develop innovative strategies for the design and synthesis of novel compounds with potential applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 72630-78-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,6,3 and 0 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 72630-78:
(7*7)+(6*2)+(5*6)+(4*3)+(3*0)+(2*7)+(1*8)=125
125 % 10 = 5
So 72630-78-5 is a valid CAS Registry Number.
InChI:InChI=1/C5H3ClF2N2/c1-2-3(6)4(7)10-5(8)9-2/h1H3
72630-78-5Relevant articles and documents
THE FLUORINATION OF 2,4,5-TRICHLORO-6-METHYLPYRIMIDINE; EXPERIMENTAL STUDY AND CNDO/2 CALCULATION
Wei, Tang,Yi-Xing, Zhao,Zheng-Hua, Zhu,Kong-Chang, Chen
, p. 373 - 392 (1987)
A study of the kinetics and mechanism of the fluorination of 2,4,5-trichloro-6-methylpyriimidie (TCMP) to form 2,4-difluoro-5-chloro-6-methylpyrimidine (DFCMP) in polar aprotic solvents with KF or NaF has been performed.The rate constants of the fluorination under various conditions were measured.This fluorination proceeds as a pseudo-first-order consecutive reaction.The values of the activation enthalpy ΔH*, the activation entropy ΔS* and Arrhenius activation energy ΔEa were evaluated and the influence of solvents, catalysts and fluorinating agents was discussed.The CNDO/2 method has been applied to the calculation of the reaction path of the fluorination and the energy levels of the components.The calculated results agree well with experimental observation.
