72702-57-9

Basic information

• Product Name: 1-(2-CHLOROPHENYL)-2-BROMOETHANOL
• Synonyms: 1-(2-CHLOROPHENYL)-2-BROMOETHANOL;α-(Bro-momethyl)-2-chlorobenzenemethanol
• CAS NO: 72702-57-9
• Molecular Formula: C₈H₈BrClO
• Molecular Weight: 235.51
• Mol File: 72702-57-9.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 292.6±25.0 °C(Predicted)
• Appearance: /
• Density: 1.617±0.06 g/cm3(Predicted)
• PKA: 12.63±0.20(Predicted)
• CAS DataBase Reference: 1-(2-CHLOROPHENYL)-2-BROMOETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-CHLOROPHENYL)-2-BROMOETHANOL(72702-57-9)
• EPA Substance Registry System: 1-(2-CHLOROPHENYL)-2-BROMOETHANOL(72702-57-9)

Safety Data

• Hazardous Substances Data: 72702-57-9(Hazardous Substances Data)

Usage

General Description

1-(2-chlorophenyl)-2-bromoethanol is a chemical compound with the molecular formula C8H8BrClO. It is a white to light yellow solid that is used in the production of pharmaceuticals and other organic compounds. 1-(2-CHLOROPHENYL)-2-BROMOETHANOL is known for its antimicrobial and antifungal properties, and is used in the manufacturing of disinfectants and preservatives. It is also used in the synthesis of other chemical compounds, such as esters and ethers, and is considered to be a versatile building block in organic chemistry. However, it is important to handle this compound with caution, as it is classified as a hazardous substance and can cause irritation to the skin, eyes, and respiratory system.

Upstream product

• 2039-87-4 2-chlorostyrene 
• 2142-68-9 1-(2-chlorophenyl)ethanone 
• 5000-66-8 2-chlorophenacyl bromide 

Downstream Products

• 56203-04-4 1-(2-chlorophenyl)-2-{[2-(phenylacetamido)ethyl]amino}ethanol 
• 333309-74-3 (E)-1-(2'-chlorophenyl)-2-bromoethylene 
• 187463-09-8 (Z)-1-(2-bromovinyl)-2-chlorobenzene 
• 1608496-87-2 C₁₉H₁₉ClN₂O₂ 
• 1608496-96-3 C₂₄H₂₇ClN₂O₄ 
• 1212322-23-0 2-bromo-1-(2-chlorophenyl)ethan-1-ol 
• 41570-61-0 tulobuterol 
• 1613220-26-0 C₂₄H₂₈BrClN₂O₄ 
• 142363-73-3 2-(2-chlorophenyl)-4-n-propylmorpholine 
• 142363-69-7 6-(2-chlorophenyl)-4-n-propylmorpholin-3-one 
• 142363-65-3 1-(2-chlorophenyl)-2-(n-propylamino)ethanol 
• 62717-50-4 o-chlorostyrene oxide 

Relevant articles and documents

Tulobuterol crystal form and preparation method thereof

The invention provides a tulobuterol crystal form and a preparation method thereof. The preparation method comprises the following steps of: dissolving tulobuterol in ethyl acetate and other good solvents, dropwisely adding n-heptane and other poor solvents into the system, filtering, taking the filter cake, and drying the filter cake to obtain the tulobuterol crystal form crystal. The crystal form is high in purity and good in stability, has superiority in process production, and is suitable for long-term storage in the preparation process.

INHIBITORS OF GLI1 AS THERAPEUTIC AGENTS

This disclosure relates to compounds (I), pharmaceutical compositions comprising them, and methods of using the compounds and compositions for treating diseases related to glioma-associated oncogene (Gli) expression. More particularly, this disclosure relates to bicyclic compounds and pharmaceutical compositions thereof, methods of inhibiting Gli expression with these compounds, and methods of treating diseases related to Gli expression.

Method for synthesizing tulobuterol

The invention discloses a method for synthesizing tulobuterol. According to the method, 1-(2-chlorophenyl)-2-bromoethanone (compound 3) and 1-(2-chlorophenyl)-2,2-dibromoethanone (compound 10) can besimultaneously utilized to synthesize the tulobuterol. In an original route, the compound 10 is a by-product of synthesis of the compound 3, and about 10-15% of the compound 10 is not fully utilized.The method provided by the invention can improve the synthesis yield of the tulobuterol, is simple to operate, is environmentally friendly, is low in cost and is suitable for industrial production.