7272-58-4

Basic information

• Product Name: 4,5,6,7-tetrahydro-3-methyl-4-oxo-indole-2-carboxylicaciethylester
• Synonyms: 4,5,6,7-tetrahydro-3-methyl-4-oxo-indole-2-carboxylicaciethylester;4,5,6,7-Tetrahydro-3-methyl-4-oxo-indole-2-carboxylic acid ethyl ester;3-Methyl-4-oxo-4,5,6,7-tetrahydro-1H-indole-2-carboxylic acid ethyl ester
• CAS NO: 7272-58-4
• Molecular Formula: C₁₂H₁₅NO₃
• Molecular Weight: 221.2524
• Mol File: 7272-58-4.mol
• Article Data: 5

Chemical Properties

• Melting Point: 165-167 °C(Solv: ethanol (64-17-5))
• Boiling Point: 428.2°Cat760mmHg
• Flash Point: 212.8°C
• Appearance: /
• Density: 1.217g/cm³
• Vapor Pressure: 1.54E-07mmHg at 25°C
• Refractive Index: 1.56
• PKA: 14.45±0.20(Predicted)
• CAS DataBase Reference: 4,5,6,7-tetrahydro-3-methyl-4-oxo-indole-2-carboxylicaciethylester(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5,6,7-tetrahydro-3-methyl-4-oxo-indole-2-carboxylicaciethylester(7272-58-4)
• EPA Substance Registry System: 4,5,6,7-tetrahydro-3-methyl-4-oxo-indole-2-carboxylicaciethylester(7272-58-4)

Safety Data

• Hazardous Substances Data: 7272-58-4(Hazardous Substances Data)

Usage

General Description

4,5,6,7-tetrahydro-3-methyl-4-oxo-indole-2-carboxylicaciethylester is a chemical compound that falls under the category of indole derivatives. It is a synthetic substance, commonly used in pharmaceutical research as a building block for the creation of new drugs due to its diverse range of biological activities. 4,5,6,7-tetrahydro-3-methyl-4-oxo-indole-2-carboxylicaciethylester has been found to exhibit antibacterial, antifungal, and antiviral properties, making it a valuable component in the development of medications for various infections. Additionally, its potential role in promoting anti-inflammatory and analgesic effects has attracted attention in the field of drug discovery and development. Overall, 4,5,6,7-tetrahydro-3-methyl-4-oxo-indole-2-carboxylicaciethylester holds promise for its therapeutic applications and continues to be a subject of interest in scientific research.

InChI:InChI=1/C12H15NO3/c1-3-16-12(15)11-7(2)10-8(13-11)5-4-6-9(10)14/h13H,3-6H2,1-2H3

Upstream product

• 6135-22-4 3-(dimethylamino)cyclohex-2-en-1-one 
• 5408-04-8 ethyl 2-hydroxyimino-3-oxobutanoate 
• 6829-41-0 diethyl oximinomalonate 
• 504-02-9 1,3-cylohexanedione 
• 110774-86-2 (E)-2-(3-Oxo-cyclohex-1-enylamino)-but-2-enoic acid ethyl ester 
• 141-97-9 ethyl acetoacetate 

Downstream Products

• 6577-89-5 3-Methyl-4-oxo-4,5,6,7-tetrahydro-indol-2-carbonsaeure 
• 129689-89-0 benzyl 4-(2-ethoxycarbonylethyl)-3-methyl-5-<(3-methyl-4-oxo-4,5,6,7-tetrahydro-1H-indol-2-yl)methyl>-1H-pyrrole-2-carboxylate 
• 84990-26-1 2-amino-8-carbethoxy-7,9-dimethyl-4-oxo-3,5,6,7-tetrahydropyrimido<6,5-c>indole 
• 84990-25-0 2,5-dicarbethoxy-1,3-dimethyl-4-oxo-4,5,6,7-tetrahydroindole 
• 84990-27-2 2-amino-7-carbethoxy-4,5-dihydro-6,8-dimethyl-6H-pyrrolo<3,2-c>benzothiazole 

Relevant articles and documents

Thiopyrano[2,3-e]indol-2-ones: Angelicin heteroanalogues with potent photoantiproliferative activity

A new class of compounds, the thiopyrano[2,3-e]indol-2-ones, bioisosters of the angular furocoumarin angelicin, was synthesized with the aim of obtaining new photochemotherapeutic agents. In particular 7,8-dimethyl-thiopyranoindolone 6c s showed a remarka

Synthesis of ethyl pyrrole-2-carboxylates: A regioselective cyclization of enaminones under knorr-type conditions

A regioselective formation of ethyl pyrrole-2-carboxylates 4 and 5 is effected by reductive condensation of enaminones 1a-f and ethyl 2-oximinoacetoacetate 2. The structures of the products have been delineated by spectroscopic methods.

Photochemical Heterocyclization of Functionalized Dienamines

A series of functionalized dienamines were prepared by base-catalyzed isomerisation of N-vinylaziridines.Photochemical cyclization of these N-substituted dienamines yielded predominantly pyrroline derivatives.